a rapid and sensitive liquid chromatography–tandem mass spectrometry (lc-ms) method for the estimation of enalapril and enalaprilat in human plasma. detection of analytes was achieved by tandem mass spectrometry with electrospray ionization (esi) interface in positive ion mode was operated under the multiple-reaction monitoring mode. sample pretreatment involved in a one-step protein precipitat...

Citation: Petras D, Koester I, Da Silva R, Stephens BM, Haas AF, Nelson CE, Kelly LW, Aluwihare LI and Dorrestein PC (2017) High-Resolution Liquid Chromatography Tandem Mass Spectrometry Enables Large Scale Molecular Characterization of Dissolved Organic Matter. Front. Mar. Sci. 4:405. doi: 10.3389/fmars.2017.00405 High-Resolution Liquid Chromatography Tandem Mass Spectrometry Enables Large Sca...

1. Armstrong VW, Oellerich M. New developments in the immunosuppressive drug monitoring of cyclosporine, tacrolimus, and azathioprine. Clin Biochem 2001;34:9–16. 2. Kahan BD, Keown P, Levy GA, Johnston A. Therapeutic drug monitoring of immunosuppressant drugs in clinical practice. Clin Ther 2002;24:330–50. 3. Oellerich M, Armstrong VW. Two-hour cyclosporine concentration determination: an appro...

an open-label, single-dose, randomized, 2-way crossover study was conducted in fasted healthy iranian male volunteers. eligible participants randomly assigned in a 1:1 ratio to be given one tablet of the test or reference formulation, followed by a 2-week washout period and administration of the exchange formulation. a quick and susceptible liquid chromatography–tandem mass spectrometry (lc-ms)...

Although generating large amounts of proteomic data using tandem mass spectrometry has become routine, there is currently no single set of comprehensive tools for the rigorous analysis of tandem mass spectrometry results given the large variety of possible experimental aims. Currently available applications are typically designed for displaying proteins and posttranslational modifications from ...