objective(s):alzheimer's disease (ad) is the most common age-related neurodegenerative disorder. one of the hallmarks of ad is an abnormal accumulation of fibril forms of tau protein which is known as a microtubule associated protein. in this regard, inhibition of tau aggregation has been documented to be a potent therapeutic approach in ad and tauopathies. unfortunately, the available syn...

objective(s):breast cancer is an important leading cause of death from cancer. stathmin and tau proteins are regulators of cell motility, and their overexpression is associated with the progression and bad prognosis of breast cancer. memantine, an n-methyl-d-aspartate (nmda) receptor antagonist, is the potential inhibitor of tau protein in neurons. this study determines the effect of memantine ...

tau is one of several types of microtubule-associated proteins (maps), responsible for the assembly and stability of microtubule networks that is present only in neurons and predominantly localized in axons which its functions are tightly regulated by phosphorylation. via as yet unknown mechanisms, tau becomes hyperphosphorylated and accompanies with neuronal degeneration, loss of synapses, abe...

a topoframe, denoted by $l_{ tau}$,  is a pair $(l, tau)$ consisting of a frame $l$ and a subframe $ tau $ all of whose elements are complementary elements in$l$. in this paper, we define and study the notions of a$tau $-real-continuous function on a frame $l$ and the set of realcontinuous functions $mathcal{r}l_tau $ as an $f$-ring.we show that $mathcal{r}l_{ tau}$is actually a generalization ...

in this paper we define the notions of ultra and involution ideals in bck-algebras. then we get the relation among them and other ideals as (positive) implicative, associative, commutative and prime ideals. specially, we show that in a bounded implicative bck-algebra, any involution ideal is a positive implicative ideal and in a bounded positive implicative lower bck-semilattice, the notions of...

An involution or anti-involution is a self-inverse linear mapping. In this paper, we will present two real quaternion matrices, one corresponding to a real quaternion involution and one corresponding to a real quaternion anti-involution. Moreover, properties and geometrical meanings of these matrices will be given as reflections in R.

This paper aims to investigate properties of strictly involution binary relations, which are generalizations of the classical notions of binary relations. We study the concepts of involution spanning subsets and give some examples related to different involution binary relations. Moreover, the involution independence with code is also considered in this paper.

Building on the algebraic framework developed by Hendricks, Manolescu, and Zemke, we introduce study a set of Floer-theoretic invariants aimed at detecting corks. Our obstruct extension given involution over any homology ball, rather than particular contractible manifold. Unlike previous approaches, do not utilize closed 4-manifold topology or contact topology. Instead, adapt formalism local eq...

Let $A$ be a Banach ternary algebra over a scalar field $Bbb R$ or $Bbb C$ and $X$ be a ternary Banach $A$--module. Let $sigma,tau$ and $xi$ be linear mappings on $A$, a linear mapping $D:(A,[~]_A)to (X,[~]_X)$ is called a Lie ternary $(sigma,tau,xi)$--derivation, if $$D([a,b,c])=[[D(a)bc]_X]_{(sigma,tau,xi)}-[[D(c)ba]_X]_{(sigma,tau,xi)}$$ for all $a,b,cin A$, where $[abc]_{(sigma,tau,xi)}=ata...