OBJECTIVE Transcatheter aortic valve implantation (TAVI) has emerged as an alternative treatment to aortic valve replacement (AVR) for selected patients with severe aortic stenosis. The present systematic review was conducted to analyze the cost-effectiveness of this novel technique within reimbursed healthcare systems. METHODS Two reviewers used 7 electronic databases from January 2000 to No...

BACKGROUND Incidence of cerebral microinfarcts is higher after transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR). It is unknown whether these lesions persist and what direct impact they have on health-related quality of life. The objective was to identify predictors of cerebral microinfarction and measure their effect on health-related quality...

AIMS Knowledge of longitudinal left and right ventricular (LV and RV) function after transcatheter aortic valve implantation (TAVI) is scarce. We hypothesized that the longitudinal systolic biventricular function in aortic stenosis (AS) patients is affected differently by TAVI and surgical aortic valve replacement (SAVR). METHODS AND RESULTS Thirty-three AS patients (all-TAVI group, age 81 ± ...

At follow-up, New York Heart Association functional class III or IV was present in 10% of the population. Mean transaortic gradients decreased from 44.3 17.2 mm Hg (before TAVI) to 10.2 5.2 mm Hg (after TAVI), and aortic valve area increased from 0.6 0.2 cm (before TAVI) to 1.9 0.3 cm (after TAVI; p 0.001 for oth comparisons). Perivalvular leak of 2 or more was present in 5% of patients. No cas...

Objective International guidelines recommend the use of dual antiplatelet therapy (DAPT) after transcatheter aortic valve implantation (TAVI). The recommended duration of DAPT varies between guidelines. In this two-part study, we (1) performed a structured survey of 45 TAVI centres from around the world to determine if there is consensus among clinicians regarding antiplatelet therapy after TAV...

OBJECTIVES To evaluate longitudinal left and right ventricular function (LVF and RVF) after transcatheter aortic valve implantation (TAVI) as compared to surgical aortic valve replacement (SAVR) and LVF and RVF after TAVI by the transfemoral (TF) or transapical (TA) approach. BACKGROUND Knowledge about differences in recovery of LVF and RVF after TAVI and SAVR is scarce. METHODS Sixty patie...

PARTNER (Placement of Aortic Transcatheter Valve Trial) remains the only randomized-controlled trial to compare transcatheter aortic valve implantation (TAVI) with surgical aortic valve replacement (AVR) for patients with severe aortic stenosis (1–3). The survival, symptomatic, and cost benefits of TAVI compared to medical therapy in inoperable patients has been previously demonstrated (2,4). H...

AIMS To assess treatment decision and outcome in patients referred for transcatheter aortic valve implantation (TAVI) in addition to predictive factors of mortality after TAVI. METHODS Three-centre prospective observational study including 358 patients. Endpoints were defined according to the Valve Academic Research Consortium. RESULTS Of the 358 patients referred for TAVI, TAVI was perform...

BACKGROUND While transcatheter aortic valve implantation (TAVI) has traditionally been supported intraprocedurally by transoesophageal echocardiography (TOE), transthoracic echocardiography (TTE) is increasingly being used. We evaluated echocardiographic imaging characteristics and clinical outcomes in patients who underwent TTE during TAVI (TTE-TAVI). METHODS AND RESULTS A select team of ded...

BACKGROUND The proven efficacy of transcatheter aortic valve implantation (TAVI) in high-risk patients is leading to the expansion of its indications toward lower-risk patients. However, this shift is not supported by meaningful evidence of its benefit over surgical aortic valve replacement (SAVR). This analysis aims to describe outcomes of TAVI versus SAVR in low-risk patients. METHODS AND R...