A lot of pathological conditions could provoke damaging of the innervations of the cornea and lead to persistent epithelial defect (PED). AMX is lyophilized preparation of amniotic membrane (AM), which contains biological components and efficacy of AM for treatment of the corneal surface defects. In processing all the substances essential for biological effects of AM are preserved (growth facto...

OBJECTIVES To quantify the risk glaucoma patients are at, having their eye treatment omitted on admission to non-ophthalmic wards at a tertiary referral centre. DESIGN A criterion audit surveying all adult inpatients on 13 wards at a tertiary referral centre on two separate dates to reduce convenient sample bias. SETTING A tertiary referral centre in the West Midlands of England. PARTICIP...

5 Among the myriad of issues facing glaucoma patients and clinicians alike are the sizable barriers to ocular drug delivery. Most existing glaucoma medications are hypotensive agents administered as topical eye drops, whose frequent and burdensome administration leads to patient adherence rates considered to be “pharmacologically insufficient” in over 75% of patients1. Even when eye drops are a...

A variety of compounds which are involved in the management of diseases of non-infectious aetiology have shown some antimicrobial activity in vitro, against bacteria and other microorganisms (13). Such compounds are called ìnon-antibioticsî. By the end of the nineteenth century the dyes were known to possess antimicrobial activity. Paul Ehrlich used methylene blue ñ one of phenothiazines compou...

OBJECTIVE To assess the awareness among chest physicians, ophthalmologists and patients about use of eye drops with particular reference to beta blockers such as timolol as an agent of aggravating breathlessness in predisposed subjects. DESIGN Cross-sectional study. METHOD A survey of 20 chest physicians, 20 ophthalmologists and 200 patients suffering from obstructive airway disease was con...

OBJECTIVE To determine the efficacy and safety of azithromycin 1.5% eye drops in a paediatric population with purulent bacterial conjunctivitis. PATIENTS AND METHODS This was a multicentre, international, randomised, investigator-masked study in 286 children with purulent discharge and bulbar conjunctival injection. Patients received either azithromycin 1.5% eye drops (twice daily for 3 days)...

7701 Abstracts of papers. (7702-7954) lA 7955 Frequency-dependent pharmacological and physiological effects on the rat ventricle strip. J. M. Benforado 86 7956 The effects of tetrahydrozoline (tyzine) on cardiac and vasomotor functions. D. E. Hutcheon, A. Scriabine, V. N. Niesler 101 7957 The convulsant effect of hydrazides and the antidotal effect of anticonvulsants and metabolites. E. H. Jenn...

In the pharmaceutical industry, there are increasing requirements for analytical methods in quality assessment for the production of drugs. In this investigation, ion mobility spectrometry (IMS) was used for the rapid qualitative separation and identification of active ingredients in generic over-the-counter drugs and food additives in beverages. The active ingredients determined in drugs were ...

The electrochemical behavior of tetrahydrozoline (THZ) was explored by cyclic voltammetry and differential pulse voltammetry. A well-defined peak at 915 mV using gold nanomodified electrode (AuNPts/CP) in presence of sodium dodecyl sulphate (SDS) was detected. Different buffers, pH and scan rates on oxidation peak current were studied. Linear calibration curve was achieved in the range of 1.99×...