efficiency of enzymes which are used in industrial or environmental applications is highly dependent on their thermal stability. in this study, the stability of dfpase has been evaluated after introducing disulfide bonds to the structure. the results obtained from a series of protein design software were subjected to molecular dynamics simulation at different temperature to test the performance...

The paper presents a methodology for simulating the static and dynamic performance of integrated circuits in the presence of electro-thermal interactions on the integrated circuit die. The technique is based on the coupling of a finite element method (FEM) program with a circuit simulator. In difference to other known simulator couplings a time step algorithm is used. Its implementation into si...

As power density of microprocessors is increasing rapidly and resulting in high temperatures, the reliability of chips is greatly affected, making thermal simulation a necessity for CPU designs. Current thermal simulation methods (for example, the HotSpot simulator) are very useful, but are still inefficient when performing thermal analysis for long simulation times. In this paper, we propose a...

The heat extraction efficiency of a cylindrical diffuser can be optimized by applying differential geometry [J.-P. Huang, Theoretical Thermotics: Transformation Thermotics and Extended Theories for Thermal Metamaterials (Springer, 2020)], in order to find metamaterial design. That done coupling thermally insulating material (polytetrafluoroethylene) with high thermal conductivity (copper) where...

Heat generation in an exothermic reaction during the curing process and low thermal conductivity of the epoxy resin produces high peak temperature and temperature gradients which result in internal and residual stresses, especially in large epoxy samples. In this paper, an optimization algorithm was developed and applied to predict the thermal cure cycle to minimize the temperature peak and the...

In this work, thermal transport in nanocrystalline materials is studied using large-scale equilibrium molecular dynamics simulation. Nanocrystalline materials with different grain sizes are studied to explore how and to what extent the size of nanograins affects the thermal conductivity and specific heat. Substantial thermal conductivity reduction is observed and the reduction is stronger for n...

Using thermal spraying various surface coatings consisting of different material compositions can be manufactured. Besides different solid phases the resulting coating microstructure often contains a non-negligible amount of pores. In this context a roller burnishing process with a hydrostatic ball-point-tool is examined to compact the thermally sprayed coating, thereby reducing porosity. The r...

An original approach is presented to the timedependent thermal modelling of complex 3-dimensional electronic systems, from metallised power FETs and MMICs, though MCMs, up to circuit board level. This method o ers a powerful alternative to conventional numerical thermal simulation techniques. In contrast to semi-analytical Fourier approaches involving DFT-FFT, the method is based on explicit, f...