More than 40% of allergic patients suffer from grass pollen allergy. Phl p 1, the major timothy grass pollen allergen, belongs to the cross-reactive group 1 grass pollen allergens that are thought to initiate allergic sensitization to grass pollen. Repeated allergen encounter boosts allergen-specific IgE production and enhances clinical sensitivity in patients. To investigate immunological mech...

Allergen-specific immunotherapy (SIT) is the only allergen-specific treatment for allergy. It can prevent progression of the disease and has a long-lasting therapeutic effect. Since SIT is allergen-specific, the identification of the disease-eliciting allergen is an essential prerequisite for the accurate prescription of treatment. Diagnostic tests based on allergen extracts consist of mixtures...

Peanut and tree-nut allergies have increased dramatically in prevalence, especially children. Historically, children with food been treated through strict avoidance of the allergen. Recently, an oral preparation peanut allergen (Palforzia) was approved for immunotherapy (ie, desensitization) 4 to 17 years old. This article reviews its role allergies.

Abstract The immunomodulatory properties of probiotics are particularly important at the establishment Th 1-Th 2immune balance early in life. A skewing to response driven by dendritic cell regulation can lead airway alteration during respiratory allergy and virus infection. Previous work from our lab have determined that oral supplementation mice with Lactobacillus johnsonii (Lj) resulted be pr...

Preparation of high quality allergen extracts is essential for the diagnosis and immunotherapy of allergic disorders. Standardization of allergen extracts concerns determination of the allergen unit, development of reference material and measurement of the overall IgE binding capacity of an allergen extract. Recently, quantification of individual allergens has been the main focus of allergen st...

background: allergy to saffron (crocus sativus) pollen has been described in people involved in processing of saffron flower stamens. profilins have been identified as a pan-allergen in different plant pollens and foods. this molecule is an actin-binding pro-tein with a molecular weight of 12-16 kda found in eukaryotic species. objective: the aim of this study was to generate monoclonal antibod...

BACKGROUND Rat allergen has proved to be an important cause of IgE-mediated hypersensitivity in the occupational setting. The prevalence and significance of rat allergen in homes has not been studied. OBJECTIVE The purpose of this study was to determine the prevalence of rat allergen in the homes of inner-city children with asthma and to examine the relationship between rat allergen exposure,...

abstract the genus aspergillus, which consists of a few hundred opportunistic mold species found in various climatic conditions, causes diseases including localized infections, fatal diseases, allergic responses, and inhaled conidia in humans. herein, we present an overview of the most common diseases and allergic infections caused by aspergillus species and their associated health hazards in v...

the prevalence of allergic disorders has increased markedly throughout the world over the past three decades. it seems probable that the increased prevalence is real because longitudinal studies have shown a rapid exponential increase in allergic disor¬ders. in order to determine the prevalence of type 1 allergy in patients with allergic disorders in sistan-blouchestan province, in the southeas...

patients and methods in this cross sectional study, 295 volunteers with the signs and symptoms of allergic diseases who referred to the khuzestan jahad daneshgahi medical center in ahvaz during 2010 were investigated. all patients were subjected to skin prick test (spt) with common allergenic extracts. data were analyzed by spss-18 software using chi square test. results seventy subjects, compr...