Thesis Abstract Background: Anti-cancer chemotherapy although effective it inducesserious  adverse effects. In addition, cancer cells can develope resistance to chemotherapy. Aim: The clinical application of cisplatin is limited by severe side effects associated with high applied doses. synergistic effect a combination treatment low dose the natural alkaloid α-solanine on human hepatocellular c...

approved:

The interest in data provenance and trust has been increasing in the last years and the community is putting now a lot of effort in finding a standard model representation. The W3C provenance incubator group is focused on this area, analyzing different provenance models and making mappings between them and the Open Provenance Model (OPM)[1], which is the model they intend to make the standard. ...

Thesis Abstract Background: Metformin, an anti-diabetic drug, has been found in recent studies to have multifactorial efffects different clinical settings. Aim: Peripheral sensory neuropathy is the most prominently reported adverse effect of oxaliplatin. This study was conducted evaluate metformin role oxaliplatin-induced neuropathy. Patients and Methods: From November 2014 May 2016, 40 patient...