Six new complexes of palladium(II) with a general formula [Pd(L)2Cl2], where L = 2-amino-4-(4-subsistuted phenyl)thiazole. The palladium were prepared by the reaction phenyl)thiazole ligands Bis(benzonitrile)palladium(II) dichloride in chloroform solvent at molar ratio Pd:L=1:2. resulting characterized magnetic susceptibility, conductivity measurements, infrared, 1H NMR and thermo gravimetric a...

There are other factors which might be studied in relation to the beneficial effect of excess thiazole in the presence of limiting amounts of thiamin or molecularly equivalent quantities of its intermediates. However, it appears clear that the thiazole effect exists under many variations of the conditions under which Phycomyces might be grown in laboratory practice. This is important in the use...

abstract       background and objectives: antibiotic resistance in bacteria has actuated researchers toward evaluating many new antibacterial compounds of which are the thiazoles. in this research the inhibitory effects of novel thiazole derivatives were unraveled on staphylococcus aureus, streptococcus agalactiae, pseudomonas aeruginosa and klebsiella pneumoniae and oxothiazole liver toxicity ...

BACKGROUND AND OBJECTIVES Bacterial resistance to antibiotics has motivated the researchers to evaluate the novel anti-bacterial compounds such as some thiazole and imidazole derivatives. Thereby, in this work, we investigated the anti-bacterial effects of one new thiazole and two new imidazole derivatives on Bacillus cereus, Listeria monocytogenes, Escherichia coli, Salmonella typhimurium, Pro...

The current study examined the bioactivation potential of ghrelin receptor inverse agonists, 1-{2-[2-chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]2,7-diazaspiro[3.5]nonan-7-yl}-2-(imidazo[2,1-b]thiazol-6yl)ethanone (1) and 1-{2-[2-chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]-2,7diazaspiro[3.5]nonan-7-yl}-2-(2-methylimidazo[2,1-b]thiazol-6-yl) ethanone (2), containing a fused imidazo[2,1-b]thiazole motif i...

We describe a spectroelectrochemical approach to accelerated electrochemical stability studies of conjugated polymers under oxidative stress. The polaron stabilities of alternating copolymers based on (i) thiophene and thiazole, namely PTTz, and (ii) bithiophene and thiazole, namely PTTTz, are compared in neat films with that of P3HT. P3HT is found to be the most stable whilst PTTz is found to ...

The current study examined the bioactivation potential of ghrelin receptor inverse agonists, 1-{2-[2-chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]-2,7-diazaspiro[3.5]nonan-7-yl}-2-(imidazo[2,1-b]thiazol-6-yl)ethanone (1) and 1-{2-[2-chloro-4-(2H-1,2,3-triazol-2-yl)benzyl]-2,7-diazaspiro[3.5]nonan-7-yl}-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone (2), containing a fused imidazo[2,1-b]thiazole motif...

A method is described to rapidly select and classify many independent near-UV irradiation-resistant Escherichia coli mutants, which include tRNA modification and RNA synthesis control mutants. One class of these mutants was found to be simultaneously deficient in thiamine biosynthesis and in the ability to modify uridine in tRNA to 4-thiouridine, known to be the target for near-UV irradiation. ...

objective(s):according to the prevalence of neoplastic diseases, there is a deep necessity for discovery of novel anticancer drugs in the field of medicinal chemistry. in the current study, a new series ofphenylthiazole derivatives(compounds 4a-4f) was synthesizedand theiranticancer activity was assessed in vitro. materials and methods:all synthesized derivatives were evaluated towards three hu...

anticonvulsant activity of 7-phenyl-5h-thiazolo[5,4-e][1,2,3,4]tetrazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepine (5) and 7-phenyl-5h-thiazolo[5,4-e][1,3,4]triazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepines (6a-d) was measured against pentylenetetrazole (ptz)-induced seizures in mice. intraperitoneal injections of different doses (12.5, 25 and 50 mg/kg, i.p.) of test compounds decreased ptz-induced seizure...