Objective: Addition of the drugs to lidocaine to induce epidural analgesia in order to elongate and enhance the analgesia has been investigated previously. The objective of this study was to compare the effects of epidurally administered xylazine either in combination of lidocaine or alone in rabbits. Design: Experimental study Animals: Twelve healthy and adult male New Zealand white strain rab...

BACKGROUND Thoracic epidural analgesia with bupivacaine resulted in clinically relevant postvoid residuals due to detrusor underactivity. This study aimed to compare the risk of bladder dysfunction with ropivacaine versus bupivacaine using postvoid residuals and maximum flow rates. Our hypothesis was that ropivacaine would result in lower postvoid residuals, because ropivacaine has been shown t...

background: accidental dural puncture during epidural blockade is a rare complication. since postdural puncture headache (pdph) is the most frequent complication, a wisely management method will also reduce the incidence of pdph. methods: five patients who had inadvertent dural puncture during the epidural procedure before hip or knee arthroplasty were included in this study. after dural punctu...

A 63 years old patient with severely impaired pulmonary function presented with bilateral lower limb vascular blockade and was operated for emergency aortobifemoral bypass. The patient was considered to be at very high risk for general anesthesia but doing the case under regional anesthesia was also challenging because of the multiple dermatomal levels needed to be anesthetized and because of t...

Effective analgesia and blockade of the perioperative stress response may improve outcome and accelerate recovery following thoracic surgery. Although different approaches can achieve the same goal, it seems that a multimodal pain management based on the use of synergistic drugs provides better analgesia. The route of administration of the postoperative analgesic drugs is important, and epidura...

OBJECTIVE To demonstrate the effectiveness of Sarapin in prolonging the action of neural blockade with improved pain relief. DESIGN Prospective, continuous, double-blind trial including 500 consecutive patients undergoing either caudal epidural injections; cervical, thoracic, lumbosacral facet joint nerve blocks; and/or intercostal nerve blocks or a combination thereof. BACKGROUND Sarapin h...

BACKGROUND Video-assisted (VATS) lung lobectomy can be associated with stronger postoperative pain than is commonly believed. It is generally accepted to introduce multimodal analgaesic strategies based on regional blockade, opioids and non-steroidal anti-inflammatory drugs. However, there is still no consensus regarding the optimal regional technique. The aim of this study was to compare the a...

BACKGROUND Adverse effects may still limit the use of continuous epidural and intravenous analgesia in surgical wards. This study postulated that postoperative epidural analgesia was more efficient, and had fewer side-effects than intravenous morphine. The aim was to investigate efficacy, adverse effects and safety of the treatments in a large patient population. METHODS During a five-year pe...

BACKGROUND Epidural blockade with local anesthetic has been shown to blunt the increase in plasma glucose concentration during and after abdominal surgery. The aim of the study was to test the hypothesis that epidural blockade inhibits this hyperglycemic response by attenuating endogenous glucose production. The authors further examined if the modification of glucose production by epidural bloc...