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Background: Children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. The aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. ...

BACKGROUND Cotton wool spots are known to be a complication in patients with thrombotic thrombocytopenic purpura or with polymyositis. CASE A 53-year-old woman developed numerous cotton wool spots around the optic disc of both eyes. OBSERVATIONS Fluorescein angiography disclosed capillary obstruction and microaneurysms in the early phase, followed by dye leakage in the late phase. Systemica...

The cause of platelet agglutination in thrombotic thrombocytopenic purpura has been an enigma. Current evidence indicates that the interaction of platelets with a platelet-aggregating factor or unusually large multimers of factor Vlllrvon Willebrand factor, or both, may cause the abnormal platelet agglutination. Recent success in the treatment of thrombotic thrombocytopenic purpura with intrave...

hepatitis a is common in children and usually is a self-limiting disease.  although extrahepatic and hematological immune manifestations following acute hepatitis a virus (hav) infection have rarely been reported, they are frequently observed in other viral hepatitis. in this paper, we report the case of a 3-year-old girl who developed immune thrombocytopenic purpura (itp) and hemolytic anemia ...

introduction: idiopathic thrombocytopenic purpura is one of the most common causes of thrombocy-topenia with varius clinical courses and different responses to its treatment modalities. therefore, we decided to evaluate the clinical course of this disease in our patients. methods: in this case series study, from march 1998 to march 2004, we evaluated 121 patients. as a first line of treatment, ...

normal 0 false false false microsoftinternetexplorer4 the association of solid tumors with idiopathic thrombocytopenic purpura (itp) is rare. however, there have been some case reports indicating an association between breast cancer and itp. in this article four patients with breast cancer and itp are mentioned. the diagnosis of breast cancer was based on the results of biopsy or surgical sampl...

conclusions: in this study, a higher rate of more severe itp in recently vaccinated young children was observed in comparison with other probable etiologies. further investigations are needed to explain this finding. results: 51 patients were enrolled in this study (mean age = 3.86 ± 1.53 months; males = 32 [62.7%]). in 33 (64.7%) patients the platelets level was below 20000 /mm3. thrombocytope...

background: the autoimmune disease known as idiopathic (immune thrombocytopenic purpura thrombocytopenic purpura (itp) is clinically defined by a low numbers of platelets in the circulation blood. this study aimed to isolate autoantibodies made against the platelet glycoproteins using platelets from healthy volunteers, to determine their specificity and further elucidate their effects on platel...

Idiopathic Thrombocytopenic Purpura (ITP) is caused by production of platelet autoantibody. Then ITP can be various viral infections, including Human Immunodeficiency Virus (HIV), Hepatitis C (HCV), cytomegalovirus, herpes simplex virus, Zika virus and others [1].