Starting with "mitochondrial Eve" in 1987, genetics has played an increasingly important role in studies of the last two million years of human evolution. It initially appeared that genetic data resolved the basic models of recent human evolution in favor of the "out-of-Africa replacement" hypothesis in which anatomically modern humans evolved in Africa about 150,000 years ago, started to sprea...

“Full House” is undoubtedly about the misunderstanding of variation in different systems. In this sense, it follows a systems-theoretic discourse relevant to many areas of human activity – how else would it be possible to discuss baseball and evolution together so persuasively? But Gould’s aim is above all to discredit the concept of “progress” in biological evolution, which he does by discussi...

It is argued that overlap between the Software Engineering and Human-Computer Interaction disciplines is part of a natural evolution that has been developing throughout the history of both fields. It is further proposed that education and training is the most effective and long-lasting solution to some of the problems of communication and efficiency that have developed. Finally, it is argued th...

Sällman Almén, M. 2012. The Membrane Proteome: Evolution, Characteristics and Classification. Acta Universitatis Upsaliensis. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 818. 35 pp. Uppsala. ISBN 978-91-554-8484-2. Membrane proteins are found in all kingdoms of life and are essential for cellular interactions with the environment. Although a large resea...

Urban form has undergone tremendous changes throughout history. These changes have stemmed from various causes. Technology has been one of the most influential forces in changing the face of cities, leaving different marks on the city form. In fact, technology has gained an increasingly more important and integrative role in bringing changes to the urban form. In addition, recent plethora of de...

PDZ domain-mediated interactions have greatly expanded during metazoan evolution, becoming important for controlling signal flow via the assembly of multiple signaling components. The evolutionary history of PDZ domain-mediated interactions has never been explored at the molecular level. It is of great interest to understand how PDZ domain-ligand interactions emerged and how they become rewired...

The purpose of this study was to investigate and compare whether the explant supernatants prepared from endometrial tissues during the proliferative phase, secretory phase and early pregnancy differ in immunosuppressive activity. Specimens of nonpregnant endometrium from hysterectomies and normal first trimester decidua following elective aspiration termination of pregnancy were obtained. ...