BACKGROUND AND PURPOSE Although the thymus is centered in the mediastinum, often a cervical component can be seen in children and young adults. The frequency of radiologically evident residual cervical thymus in older adults is not known. The purpose of our study was to determine the proportion of adults who have residual cervical thymus visible on contrast-enhanced neck CT. MATERIALS AND MET...

Antibodies to chromatographically purified rat thymus Fl histone subfractions were induced in rabbits by immunization with histone-RNA complexes. The immunological relatedness between each of the rat thymus Fl subfractions and subfractions derived chromatographically from calf thymus and rat liver Fl was determined by quantitative microcomplement fixation. The various rat thymus peaks elicited ...

Thymus is a bilobed organ usually situated in the superior mediastinum. Thymus is normally active until puberty and as age advances it undergoes considerable fibrofatty degeneration and is replaced by fatty tissue. We found a persistent thymus in an adult male cadaver aged 70 years approximately. It apparently looked healthy. Hence the objective of this study was to know the morpho-histology of...

When neonatally thymectomized CBA mice were implanted at 9 to 12 days of age with Millipore diffusion chambers (pore size, 0.1 micro) containing either syngeneic or allogeneic neonatal thymus, they were subsequently found to have the capacity to reject skin homografts and to form antibodies to sheep erythrocytes. In spite of displaying restored immune reactivity, thymectomized mice bearing thym...

Thymus seeding by T-lymphoid progenitor cells is a prerequisite for T-cell development. However, molecules guiding thymus colonization and their roles before and after thymus vascularization are unclear. Here we show that mice doubly deficient for chemokine receptors CCR7 and CCR9 were defective specifically in fetal thymus colonization before, but not after, thymus vascularization. The defecti...