Background: Imatinib mesylate is the first generation of Tyrosine kinase inhibitors (TKI) and highly effective in the treatment of chronic myeloid leukemia (CML). We aimed to evaluate thyroid function at baseline and at 1, 3, 6 and 12 months after initiation of Imatinib mesylate therapy in 20 newly diagnosed BCR-ABL positive CML patients. Methods: This study was done during 2013-2014, 20 new c...

The incidence of mole pregnancy appears to be higher in Iran than in Europe or North America. This gave us an opportunity to study a number of biochemical measurements related to the thyroid. In 14 patients with hydatiform mole, the T3 resin uptake, serum thyroxine (T4), ETR, T3 RIA, human serum TSH (hTSH) and serum human Chorinic gonadotropin (hCG) were measured. Of the 14 patients 6 sho...

background: to investigate thyroid function in preeclamptic patients in comparison with normal pregnant women. methods: in this analytical cross-sectional study free thyroxine (t4), and thyroid stimulating hormone (tsh) levels were measured in 100 preeclamptic patients and were compared with free t4 and tsh levels in 101 normal pregnant women in their third trimester of pregnancy. patients with...

background: anti-thyroid peroxidase antibody (anti-tpo antibody) is a member of thyroid autoantibodies which are important in inducing and also diagnosing autoimmune thyroid diseases. thyroid autoimmunity can cause several forms of thyroiditis and abnormal thyroid functions, ranging from hypothyroidism to hyperthyroidism. objective: to evaluate the relationship between serum levels of anti-tpo ...

The objective of this experiment was to determine the effect of long-term low-dose administration of lead (Pb) on thyroid function in sheep. In this experiment 10 healthy Iranian male sheep, aged about oneyear- old were randomly allocated into two equal groups of control (n = 5) and experiment (n = 5). Both groups were kept under the same conditions of food and environment. The treatment group ...

purpose: to evaluate the prevalence of clinical and subclinical thyroid disorders using thyroid function tests in patients with single and multiple chalazia. methods: a complete ophthalmologic examination and thyroid function tests including thyroid stimulating hormone (tsh), thyroxine (t4) and triiodothyronine (t3) were performed in 60 patients with single chalazia and 50 patients with multipl...