Background: Abortion is the interruption and/or termination of pregnancy, either spontaneously or intentionally, before fetus develops sufficiently to survive. About 80% abortions occur in first 12 weeks pregnancy. The underlying mechanism about half cases involves chromosomal abnormalities. Objective: To evaluate association between TSH, T3, T4, anti-thyroglobulin antibody and thyroid peroxida...

A case of parasitic thyroid nodule is presented. The patient was a non symptomatic 53-year-old white woman, on irregular course of L-thyroxine to treat hypothyroidism due to Hashimoto's thyroiditis. Without a history of thyroid trauma or surgery, she presented a 1.6 x 0.7 x 0.5cm right pre-laryngeal lymph node-like mass which, on ultrasonography, appeared distinct from the gland. TSH, thyroid p...

Background Lichen planus pigmentosus (LPP) is considered a chronic and progressive variant of lichen planus. Although pigmentation occurs in the sun exposed areas, the etiology remains unknown and there are no appropriate treatment guidelines. Association with thyroid disorder has been described in various disorders of pigmentation. Objective The objective of this study was to find the associat...

Background Premature ovarian failure (POF) is a disorder of multi causal etiology. Autoimmunity has been proposed as a mechanism for some cases of ovarian follicle dysfunction which is evident in POF. The aim of this study was to identify the level of auto-antibodies in POF and familial POF patients. MaterialsAndMethods In this study, auto-antibodies including anti-ovarian antibody (AOA), anti ...

patients with turner’s syndrome (ts) are at an increased risk of developing autoimmune thyroid disease (atd). the aim of this study was to determine the frequency of anti-thyroid peroxidase (anti-tpo) antibodies and atd in children and adolescent girls with ts. it also assessed the influence of karyotype on the development of thyroid disease. sixty eight patients with ts were compared with 68 a...

Hashimotos encephalopathy is an autoimmune disorder, with high titres of antithyroid peroxidase antibody, usually with a clinically and biochemically normal thyroid function. Here we present a case of hashimotos encephalopathy in a 34yr old man, who presented with acute onset of cognitive impairment on a background of psychiatric illness. Initially a probability of neuroleptic malignant syndrom...

BACKGROUND Patients with chronic autoimmune thyroiditis have impaired health-related quality of life. The thyroid gland has a high selenium concentration, and specific selenoprotein enzyme families are crucial to immune function, and catalyze thyroid hormone metabolism and redox processes in thyroid cells. Previous randomized controlled trials have found that selenium supplementation decreases ...