BACKGROUND AND PURPOSE Coronary artery disease is the leading cause of death after TIA. Reliable estimates of the risk of MI after TIA, however, are lacking. METHODS Our purpose was to determine the incidence of and risk factors for MI after TIA. We cross-referenced preexisting incidence cohorts from the Rochester Epidemiology Project for TIA (1985-1994) and MI (1979-2006) to identify all com...

BACKGROUND AND PURPOSE Transient ischemic attacks (TIAs) have been shown to be a strong predictor of subsequent stroke and death. We present the incidence and short-term prognosis of TIA within a large population with a significant proportion of minorities with out-of-hospital TIA. METHODS TIA cases were identified between July 1, 1993 and June 30, 1994 from the Greater Cincinnati/Northern Ke...

Background and Purpose—Transient ischemic attack (TIA) diagnosis is frequently difficult in clinical practice. Noncerebrovascular symptoms are often misclassified as TIA by nonspecialist physicians. Clinical prediction rules such as ABCD improve the identification of patients with TIA at high risk of early stroke. We hypothesized that the ABCD score may partly improve risk stratification due to...

background all conditions that interfere with blood flow at any level within the portal system can lead to portal hypertension. for better management of this disorder, it is important to determine the underlying cause. in previ­ous studies, extra-hepatic disorders have been reported as the main cause of portal hypertension in children. in this study, we investigate the under­lying causes of por...

Patients during early period after the onset of transient ischemic attack (TIA) are at high risk of stroke. Therefore, TIA in acute setting should be recognized to be an emergency requiring immediate evaluation and starting treatment. There is no meaning to differentiate TIA in acute setting from acute ischemic stroke (AIS) only by the duration of symptoms. Acute TIA and AIS are on the same spe...

Terpenoid indole alkaloid (TIA) biosynthesis in Catharanthus roseus is a complex and highly regulated process. Understanding the biochemistry and regulation of the TIA pathway is of particular interest as it may allow the engineering of plants to accumulate higher levels of pharmaceutically important alkaloids. Toward this end, we generated a transgenic C. roseus hairy root line that overexpres...

BACKGROUND AND PURPOSE Some patients diagnosed with transient ischemic attack (TIA) in the emergency department may actually have alternative diagnoses such as seizure, migraine, or other nonvascular spells. The ABCD2 score has been shown to predict subsequent risk of stroke in patients with TIA diagnosed by emergency physicians, but perhaps high ABCD2 scores simply separate those patients with...

BACKGROUND AND PURPOSE There is limited information on outcomes from rapid access transient ischemic attack (TIA) clinics. We present 4-year outcomes of TIAs, strokes, and mimics from a UK TIA clinic database. METHODS All patients referred between April 2010 and May 2012 were retrospectively identified and outcomes determined. End points were stroke, myocardial infarction, any vascular event ...

OBJECTIVE To identify key barriers and facilitators to the delivery of guideline-based care of patients with TIA in the national Veterans Health Administration (VHA). METHODS We conducted a cross-sectional, observational study of 70 audiotaped interviews of multidisciplinary clinical staff involved in TIA care at 14 VHA hospitals. We de-identified and analyzed all transcribed interviews. We i...

BACKGROUND AND PURPOSE The occurrence of a transient ischemic attack (TIA) increases an individual's risk for subsequent stroke. The objectives of this study were to determine clinical features of patients with TIA associated with impending (≤7 days) stroke and to develop a clinical prediction score for impending stroke. METHODS We conducted a prospective cohort study at 8 Canadian emergency ...