JCB • VOLUME 186 • NUMBER 2 • 2009 166 E pithelia come in all shapes and sizes. The cells themselves can be columnar, cuboidal, or squamous in shape, whereas the tissue as a whole can take up a variety of forms. Drosophila imaginal discs, for example, are fl attened epithelial sacs that develop into different adult organs and appendages, such as the eye and wing. Matt Gibson began his scientifi...

The lymphatic system provides the context for the immune system cells and setting for their interactions as described by immunological theory. A previously defined and elaborated lymphoid tissue model is proposed as a general lymphoid-tissue inspired information processing architecture, with specific information processing and information transmission constraints imposed on different tissue typ...