نتایج جستجو برای: to assess heritability

تعداد نتایج: 10618307  

Journal: :Journal of child psychology and psychiatry, and allied disciplines 2012
Diane J Lamb Christel M Middeldorp Catarina E M Van Beijsterveldt Dorret I Boomsma

BACKGROUND Internalizing and externalizing problem behavior at school can have major consequences for a child and is predictive for disorders later in life. Teacher ratings are important to assess internalizing and externalizing problems at school. Genetic epidemiological studies on teacher-rated problem behavior are relatively scarce and the reported heritability estimates differ widely. A uni...

2016
Kristine Marceau Minni T B McMaster Taylor F Smith Joost G Daams Catharina E M van Beijsterveldt Dorret I Boomsma Valerie S Knopik

A literature search was conducted to identify articles examining the association of chorionicity (e.g., whether twins share a single chorion and thus placenta or have separate chorions/placentas) and genetics, psychiatry/behavior, and neurological manifestations in humans twins and higher-order multiples. The main aim was to assess how frequently chorionicity has been examined in relation to he...

2016
Gaurav Bhatia Alexander Gusev Po-Ru Loh Hilary Finucane Bjarni J. Vilhjálmsson Stephan Ripke Shaun Purcell Eli Stahl Mark Daly Teresa R de Candia Sang Hong Lee Benjamin M Neale Matthew C. Keller Noah A. Zaitlen Bogdan Pasaniuc Nick Patterson Jian Yang Alkes L. Price

Genome-wide significant associations generally explain only a small proportion of the narrow-sense heritability of complex disease (h). While considerably more heritability is explained by all genotyped SNPs (hg ), for most traits, much heritability remains missing (hg 2 < h). Rare variants, poorly tagged by genotyped SNPs, are a major potential source of the gap between hg 2 and h. Recent effo...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد شاهرود - دانشکده پزشکی 1390

nitric oxide (no) is a small molecule synthesized by most of mammalian cells with diverse biological activities including vasodilatation, host defense and wound healing. impaired wound healing is a common occurrence among diabetics and patients receiving glucocorticoid therapy. on the other hand the application of laser in biomedical area have been increased. thus, the current studies were desi...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده علوم 1392

gol-e-gohar iron ore mine of sirjan in southern part of iran is a large open pit that operates below the groundwater table and during mining operation, dewatering is required to prevent operation processes from flooding. current operation is going on by digging wells in or out of the pit and pumping to prevent flooding. as a result of the former dewatering operation a vast deep cone of depressi...

Journal: :Animal : an international journal of animal bioscience 2013
K Krag L L Janss M M Shariati P Berg A J Buitenhuis

Heritability is a central element in quantitative genetics. New molecular markers to assess genetic variance and heritability are continually under development. The availability of molecular single nucleotide polymorphism (SNP) markers can be applied for estimation of variance components and heritability on population, where relationship information is unknown. In this study, we evaluated the c...

Journal: :Neuroscience and biobehavioral reviews 2010
Ting Wu Harold Snieder Eco de Geus

Individual differences in the cardiovascular response to stress play a central role in the reactivity hypothesis linking frequent exposure to psychosocial stress to adverse outcomes in cardiovascular health. To assess the importance of genetic factors, a meta-analysis was performed on all published twin studies that assessed heart rate (HR) or blood pressure (BP) reactivity to the cold pressor ...

Journal: :Biological psychiatry 2012
Gitta H Lubke Jouke Jan Hottenga Raymond Walters Charles Laurin Eco J C de Geus Gonneke Willemsen Jan H Smit Christel M Middeldorp Brenda W J H Penninx Jacqueline M Vink Dorret I Boomsma

Genome-wide association studies of psychiatric disorders have been criticized for their lack of explaining a considerable proportion of the heritability established in twin and family studies. Genome-wide association studies of major depressive disorder in particular have so far been unsuccessful in detecting genome-wide significant single nucleotide polymorphisms (SNPs). Using two recently pro...

Journal: :NeuroImage 2012
Joonkoo Park Kerby Shedden Thad A. Polk

Advances in modern neuroimaging in combination with behavioral genetics have allowed neuroscientists to investigate how genetic and environmental factors shape human brain structure and function. Estimating the heritability of brain structure and function via twin studies has become one of the major approaches in studying the genetics of the brain. In a classical twin study, heritability is est...

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