We present the clinical phenotype of a toddler who presented with vitamin D-resistant rickets, with one of the highest initial levels of alkaline phosphatase and parathyroid hormone (PTH) levels reported in the literature. The toddler had novel compound heterozygous mutations in the ligand-binding site of the vitamin D receptor and had an excellent response to calcitriol (1,25(OH)2D).

The thesis objective was to design a walking robot appropriate for testing a machine learning control system. As a robot that would learn how to walk, it was pre-maturely named Toddler. The passive dynamic walker, a class of simple robots driven by gravity and inertia, was selected as the model for the Toddler robot. Two preliminary passive walkers were explored: a three-dimensional, toy-like b...

Parent–child attunement therapy (PCAT) is a promising intervention for toddlers (aged 12–30 months) who have experienced maltreatment. PCAT has two overall purposes: (1) to strengthen caregivers’ relationship with their children; and (2) to facilitate caregivers’ learning of appropriate child management techniques. PCAT represents an adaptation of parent–child interaction therapy (PCIT), which ...

OBJECTIVE The goal was to examine whether children who screen positive for social-emotional/behavioral problems at 12 to 36 months of age are at elevated risk for social-emotional/behavioral problems in early elementary school. METHODS The sample studied (N = 1004) comprised an ethnically (33.3% minority) and socioeconomically (17.8% living in poverty and 11.3% living in borderline poverty) d...

UNLABELLED Age-based differences in fall type and neuroanatomy in infants and toddlers may affect clinical presentations and injury patterns. OBJECTIVE Our goal is to understand the influence of fall type and age on injuries to help guide clinical evaluation. DESIGN/SETTING/PARTICIPANTS Retrospectively, 285 children 0-48 months with accidental head injury from a fall and brain imaging betwe...

The start of the 2nd year is a period of transition and substantial variability among toddlers in ploy and attention abilities. This longitudinal study exomined the ontecedents of voriotion among 13-month-old toddlers in these exploratory competencies in the infonts’ own informotion-processing obilities at 5 months (indexed by visuol fixotion in the loboroton/), the infonts’ vocal and explorato...

Organic brown rice syrup (OBRS) is a sweetener frequently used as an alternative to high-fructose corn syrup in organic and health food products. In a study of children’s foods, a team of researchers discovered high levels of arsenic in toddler formula products that contained OBRS. Given evidence that arsenic accumulates in rice at high levels, the researchers suspected OBRS was the source of t...

Organic brown rice syrup (OBRS) is a sweetener frequently used as an alternative to high-fructose corn syrup in organic and health food products. In a study of children’s foods, a team of researchers discovered high levels of arsenic in toddler formula products that contained OBRS. Given evidence that arsenic accumulates in rice at high levels, the researchers suspected OBRS was the source of t...

The extent to which engaged maternal coping styles moderate the association between toddler's temperamental reactivity and mothers' sensitivity to children's negative emotions was examined in 89 mother-child dyads. Primiparous mothers completed a measure of coping styles prenatally. When toddlers were 16 months old, mothers completed a measure of perceived toddler temperament and a self-report ...