Skin fibroblasts from patients with familial dysautonomia, Duchenne muscular dystrophy and Charcot-Marie-Tooth disease show normal sensitivity to ionising radiation, as measured by post-irradiation clonal growth. Previous reports of cellular hypersensitivity to ionising radiation and other DNA-damaging agents in familial dysautonomia and Duchenne muscular dystrophy have not been confirmed.

OBJECTIVE The aim of this randomized controlled clinical trial was to investigate the effect of a new Iranian toothpaste and a commercially available toothpaste containing desensitizing agent (5% potassium nitrate) on dentine hypersensitivity in a 24-week study. MATERIALS AND METHODS Fifty healthy volunteers, who had at least two sensitive root surfaces, completed the study period. The partic...

Tooth sensitivity is a very common clinical presentation which can cause considerable concern for patients. This condition is frequently encountered by periodontists, dentists, hygienists and dental therapists. The management of this condition requires a good understanding of the complexity of the problem, as well as the variety of treatments available. This review considers the aetiology, inci...

Objective: A powder jet deposition (PJD) process can be used to create a thick hydroxyapatite (HA) layer on the human tooth surface. The purpose of this exploratory trial was to evaluate the safety and efficacy of the hydroxyapatite layer formed by a new dental treatment system for cases of caries, dentin hypersensitivity, or discolored teeth. Methods: A single facility, non-blinded study compa...

Dental hypersensitivity due to exposure of dentinal tubules under the enamel layer to saliva is a very popular and highly elusive technology priority in dentistry. Blocking water flow within exposed dentinal tubules is a key principle for curing dental hypersensitivity. Some salts used in "at home" solutions remineralize the tubules inside by concentrating saliva ingredients. An "in-office" opt...

Fixed partial denture is one of the most popular and commonly used treatment modality for replacement of missing teeth. It often involves preparation of vital abutments to support the retainers of the fixed partial denture. Full coverage restorations or retainers; involve preparation of all the tooth surfaces of the abutments. Post-cementation hypersensitivity in vital abutments is a common com...

Dentine hypersensitivity or more colloquially “sensitive teeth” is a common problem encountered in routine clinical practice. The diagnosis of it, at times, is intriguing for even the most experienced clinician. The condition, though not alarming, is important diagnostically and therapeutically because it tends to disturb the routine day to day life of the patient, often becoming troublesome du...

conclusions the characteristic features of ige-mediated food allergy are abrupt onset of clinical symptoms, which may result in a life-threatening events, and positive results of the majority of the paraclinical tests that mainly trace the specific ige to foods. moreover, non–ige-mediated food allergies present as chronic diseases and due to lack of proper diagnostic tests the similarity of the...

Background: Calcium phosphates (CPs) form hydroxyapatite (HA) in physiological solutions. These are commonly used to treat dentine hypersensitivity (DH) as they mimic the mineral composition of natural tooth. Aim: The present study aims characterise apatite formation ability a commercially available calcium phosphate TeethmateTM (TM) physiological-like media. Materials and Methods: In this stud...