To investigate the wide range of pollutants occurring in sewage sludge, an analytical method for comprehensive non-target screening is needed. To the best of our knowledge, no procedures currently exist for the full screening of organic contaminants in sewage sludge, which is the ultimate goal of this project. We developed non-discriminating sample preparation methods for gas chromatography-mas...

Background The effect of polar organic xenobiotics in the central nervous system depends on blood-brain barrier (BBB) penetration of these compounds. Newly synthesized pyridinium aldoximes (K-compounds) are promising antidotes for organophosphate intoxications. However, being highly polar, their BBB penetration is questionable. Using an in vivo model we aimed to characterize the BBB penetration...

The metabolism of plasma 5 alpha-androst-16-en-3-one (androstenone) was studied in two young boars weighing about 100 kg in which a single dose of tritiated androstenone was injected intravenously. The peripheral blood of one boar was continuously sampled for 6 h after injection; the total radioactivity per liter of plasma increased up to 14 min after the injection, and then declined rather slo...

1. Methods using t.l.c. and high-pressure liquid chromatography (h.p.l.c.) have been used to separate the complex variety of substances possessing a carbonyl function that are produced during lipid peroxidation. 2. The major type of lipid peroxidation studied was the ADP-Fe2+-stimulated peroxidation of rat liver microsomal phospholipids. Preliminary separation of the polar and non-polar product...

The valorization of the brewer's spent grain (BSG) generated in a craft beer industry was studied by subcritical water hydrolysis semi-continuous fixed-bed reactor. Temperature varied from 125 to 185 °C at constant flow rate 4 mL/min. Biomass yielded maximum 78% solubilized protein 185 °C. Free amino acids presented level 160 °C with value 55 mg free acids/gprotein-BSG. Polar acid lower tempera...

herbal medicines can be used as the potential sources of anti-oxidative compounds to help the treatment of diseases associated to oxidative stress. in this paper, the ferric reducing antioxidant power (frap) activity of four lamiaceae herbal extracts, which traditionally applied in oxidative stress related diseases, has been evaluated and total phenolics contents of these extracts determined by...

A surface sediment from Carteau cove, located at the western part of the Gulf of Fos (France), was collected and analysed to determine the lipid composition of its most polar fraction. Analyses by high performance liquid chromatography (HPLC) and thin-layer chromatography (TLC) of the polar fraction of the sediment extract revealed the presence of phospholipids (PL), with mainly phosphatidylgly...

wheat streak mosaic virus (wsmv) causes extensive economic damage to wheat (triticum aestivum l.) in many regions of the world. the present study was conducted to find out if the variations in biochemical changes in reaction to wsmv infection in f2 generation of either potentially resistant (adl-cross) or susceptible (marvdasht) cultivars are genetically inherited. a factorial experiment was em...

Arial parts of Primula genus (Primulaceae) are well known to treat various ailments in Iranian Traditional Medicine. Our preliminary studies showed that the medium polar to polar extracts of Primula auriculata had a significant cytotoxic activity and Induction of apoptosis effects on some cancerous cell lines. The current study focused on phytochemical investigation and characterization the com...

Carotenoid compositions of two freshwater Gammarus species (Crustacea: Amphipoda) and of their common acanthocephalan parasite Polymorphus minutus were characterized. The effect of carotenoid uptake by the parasite was addressed by comparing the carotenoid content of uninfected and infected female hosts. Using high-pressure liquid chromatography (HPLC), co-chromatography of reference pigments a...