Objective: This study was conducted to assess the toxicity profile of the aqueous-fermented extract of Musa paradisiaca in rats. Materials and Methods: In acute toxicity test, the rats of different groups were orally administered with a single dose of 500, 1000, 2000 and 5000 mg/kg of fermented extract of M. paradisiaca. The rats were monitored for behavioral changes, toxicity signs and mortali...

A common plant from Papua, Indonesia, called Phaleria macrocarpa (mahkota dewa), has potent therapeutic components. The aim of this study was to evaluate the toxicity level nanoherbal mahkota dewa and its effect on changes in hematology, biochemistry, electrolytes, histopathology organ. High Energy Milling (HEM) used produce dewa. LD50 determined three stages: dose orientation test (12 mice), p...

Kedayan roots are still used by the Lundayeh Dayak people as traditional medicine. This plant is one of Aristolochia sp . species whose production and distribution medicine or food supplements prohibited Food Drug Supervisory Agency Republic Indonesia because it has side effects that harmful to body. The purpose this study was determine toxicity kedayan root infusion using Brine Shrimp Lethalit...