concentrations of elements (as, co, cu, ni, mo, pb, v, cd, cr and zn) are studied in the surface sediments of bakhtegan lake, northwest of nyriz city, iran, to assess metal contamination. the average abundance order of trace elements content in bakhtegan lake sediments is cr>ni> v> zn> cu> co> as> pb> mo>cd. the comparison of trace elements concentration in bakhtegan lake sediments with toxicol...

BACKGROUND It can be difficult for occupational health professionals to assess which toxicological databases available on the Internet are the most useful for answering their questions. Therefore we evaluated toxicological databases for their ability to answer practical questions about exposure and prevention. We also propose recommended practices for searching for toxicological properties of c...

A large amount of data on the biological and toxicological activity of gases and vapors has been collected from the literature. Processes include sensory irritation thresholds, the Alarie mouse test, inhalation anesthesia, etc. It is shown that a single equation using only five descriptors (properties of the gases and vapors) plus a set of indicator variables for the given processes can correla...

This brief sketch is intended as an introduction to a series of articles 1 on bioelectrical phenomena, its purpose being to present certain fundamental facts and underlying conceptions. Early in the course of the investigation it became evident that there are great advantages in using single cells in place of tissues. The experiments were accordingly made with single (multinucleate) cells of Va...

Ginkgo biloba extract (GBE; CASRN 90045-36-6) is a commonly used herbal supplement. A comprehensive toxicological assessment by the NTP identified GBE as hepatotoxic. The constituents of GBE can vary across lots, hence the question arises as to how representative the lot tested by NTP is of other lots of GBE and by extension to what degree the results of the NTP hazard characterization are more...

In the mid-50s of last century, reports began to appear about ineffectiveness sulfonamides and antibiotics in bacterial infections. And soon widespread spread numerous strains antibiotic-resistant microorganisms was noted. The fight against drug-resistant bacteria is carried out several directions: obtaining new chemotherapeutic drugs, chemical modification known antibiotics, or use inhibitors ...

BACKGROUND Betulinic acid (BA) is a natural triterpenoid compound and exhibits a wide range of biological and medicinal properties including anti-inflammatory activity. Therefore, this theoretical investigation is performed to evaluate (a) physicochemical properties such as acid dissociation constant (pKa), distribution coefficient (logD), partition coefficient (logP), aqueous solubility (logS)...

Several indolylquinone analogues of perezone, a natural sesquiterpene quinone, were characterized in this work by theoretical methods. In addition, some physicochemical, toxicological and metabolic properties were predicted using bioinformatics software. The predicted physicochemical properties are in agreement with the solubility and cLogP values, the penetration across the cell membrane, and ...