A major paper on multiple chemical sensitivity by Professor Martin L. Pall was published October 23, 2009 as chapter XX in a prestigious reference work for professional toxicologists, “General and Applied Toxicology, 3rd Edition” (John Wiley & Sons). Multiple chemical sensitivity (MCS) is also known as chemical sensitivity, chemical intolerance and toxicant-induced loss of tolerance, with this ...

Prediction of noncancer toxicologic outcomes in rodent bioassays of 37 chemicals from the National Toxicology Program was evaluated. Using the nonneoplastic lesions noted by NTP pathologists, we evaluate both agreement in toxic lesions across experiments and the predictive value of the presence (or absence) of a lesion in one group for other groups. We compare lesions between mice and rats, mal...

The design of toxicological testing strategies aimed at identifying the toxic effects of chemicals without (or with a minimal) recourse to animal experimentation is an important issue for toxicological regulations and for industrial decision-making. This article describes an original approach which enables the design of substance-tailored testing strategies with a specified performance in terms...

m wild plants, especially when travelling abroad. The first step in acquiring such an interest is to procure a book describing the flowers to be found in some place where one is going for a holiday. Such a one is " Flowers of the Mediterranean " by Polunin and Huxley. I choose this because so many people make for that part of Europe and it is a wonderful area in which to start. Armed with such ...

Deoxynivalenol (DON) is a common Fusarium toxin in poultry feed. Chickens are more resistant to the adverse impacts of deoxynivalenol (DON) compared to other species. In general, the acute form of DON mycotoxicosis rarely occurs in poultry flocks under normal conditions. However, if diets contain low levels of DON (less than 5 mg DON/kg diet), lower productivity, impaired immunity and higher su...