There is some debate over the clinical utility of measuring serum TgAb to assess the presence of thyroid autoimmunity. To clarify the relationship between TgAb levels and thyroid autoimmunity, a histological examination of thyroid tissue was carried out on unselected living individuals with detectable serum TgAb. 146 patients with a pathological diagnosis of follicular adenoma were selected as ...

BACKGROUND Thyroid antibody testing is not routinely available in developing countries, and few studies have measured thyroid antibodies in Africans. The significance of thyroid autoimmunity in an African setting is thus unclear. AIM To determine the prevalence of thyroid antibodies in patients attending a Nigerian teaching hospital. DESIGN Prospective survey. METHODS We measured antibodi...

BACKGROUND Thyroid function changes during pregnancy, complicating the diagnosis of thyroid disorders. Maternal thyroid dysfunction has been associated with a variety of adverse outcomes. We evaluated thyroid function test results by ethnicity and week of gestation during the 2nd trimester of pregnancy. METHODS We collected 3064 blood specimens in serum tubes from Asians (13%), blacks (22%), ...

OBJECTIVES This study aimed to assess the prevalence and incidence and predictive factors of thyroid disorders (TD) in patients with impaired glucose metabolism. METHODS Prevalence of TD was calculated in patients with impaired glucose metabolism compared to healthy controls, aged over 30 years in phase 1 of the Tehran Thyroid Study (TTS). Follow up assessments were conducted every 3 yrs, aft...

Anti-C1q antibodies (anti-C1q) have been implicated in the pathogenesis of autoimmune diseases, including autoimmune thyroid disorders (AITD). The aim of this study was to evaluate the association between anti-C1q and thyroid function in pregnancy-associated AITD. In 96 pregnant women screened positive for AITD (thyroid dysfunction and/or antibodies against thyroperoxidase - TPOAb), anti-C1q we...

BACKGROUND The prevalence of thyroid dysfunction is high in Isfahan, an area of iodine sufficient in Iran. The aim of this study is to investigate the incidence of thyroid dysfunctions in adults of metropolitan Isfahan and to determine the role of thyroid autoantibodies. METHODS In a population-based cohort study in 2006-2011, we measured TSH, T4, T3, thyroid peroxidase antibody (TPOAb), and ...

OBJECTIVES Thyroid antibody positivity during pregnancy has been associated with adverse outcomes including miscarriage and preterm delivery. The aim of the study is to evaluate the obstetric outcome in pregnant women with recurrent miscarriage and their response to levothyroxine (l-T4) therapy. STUDY DESIGN AND METHODS All pregnant and non-pregnant women between 21 and 35 years of age with a...

Abstract Objective To observe the anti-inflammatory effect, as well effect on expression of microtubule-associated protein light chain 3B (LC3B) and Beclin-1 herbal cake-partitioned moxibustion in rats with experimental autoimmune thyroiditis (EAT). Methods Female Sprague-Dawley were randomly divided into a normal group modeling group. The EAT rat model was prepared by combination antigen immun...

Objective: The prevalence of thyroid dysfunction is higher in patients with diabetes, and its diagnosis could cause better diabetes management. purpose the present study to examine impact pathophysiological changes Type-2 on frequency dysfunction, autoimmunity, nodule, cancer Turkey. 
 Methods: was conducted a total 3.276 who underwent tests ultrasonography (US). demographic characteristic...