Background and objectives: Alzheimer’s disease (AD) is a neurodegenerative disorder. Nowadays, many investigations are performed to find new drugs for AD and medicinal plants are considered as one of the most important sources for developing new drugs. According to the role of oxidant agents and acetylcholinesterase enzyme (AChE) in AD, plants with antioxidant and AChE inhibition properties cou...

Palha, espiga e estigma de milho foram extraídos com água, etanol aquoso, metanol aquoso e acetato de etila, respectivamente. O conteúdo fenólico total (TPC), conteúdo flavonóide total (TFC), conteúdo cetoesteróide total (TKC) e atividades antioxidantes [atividade de sequestro de radicais, poder redutor, e poder antioxidante-redutor férrico (FRAP) de 2,2’-difenil-1-picrilhidrazil (DPPH), 2,4,6-...

Medlar is the fruit of Mespilus germanica L. in the family of Rosaceae. The present study outlines that the native medlar (Mespilus germanica L.) fruits an extremely rich source of antioxidants. In this study, antioxidant and antiradical property of medlar fruits were evaluated. Total phenolics and flavonoids amounts in lyophilized extract of medlar (LEM) fruits were calculated as gallic acid a...

A simple and efficient method for speciation and determination of iron in different water samples was developed. The method is based on ionic liquid ultrasound assisted dispersive liquid–liquid microextraction (IL-USADLLME) followed by spectrophotometric determination. Fe(II) is complexed with 2,4,6-tri(2’-pyridyl)-l,3,5-triazine (TPTZ), neutralized through ion pair formation with sodium dodecy...

PURPOSE To determine the effect of an anaesthetic with antioxidant potential, propofol, on red blood cell (RBC) antioxidant enzyme activities and RBC susceptibility to peroxidative challenge. METHODS Propofol was administered by intravenous bolus (2.5 mg.kg-1) and continuous infusion (36 and 72 ml.hr-1 in nine swine; 216 ml.hr-1 in two swine), to achieve serum concentrations between 5 and 30 ...

background and objectives:alzheimer’s disease (ad) is a neurodegenerative disorder. nowadays, many investigations are performed to find new drugs for ad and medicinal plants are considered as one of the most important sources for developing new drugs. according to the role of oxidant agents and acetylcholinesterase enzyme (ache) in ad, plants with antioxidant and ache inhibition properties coul...

BACKGROUND Roots and leaves of the Cermela Hutan (Phyllanthus gomphocarpus Hook. F) plant were studied to determine antioxidant activity, phytochemical compounds, proportion of carbohydrate, crude protein, moisture, ash, fat, total phenolic content (TPC), and total flavonoid content (TFC). MATERIAL/METHODS Ten percent (10%) aqueous extract from both Phyllanthus gomphocarpus roots (PGR) and le...

Background and objectives:Alzheimer’s disease (AD) is a neurodegenerative disorder. Nowadays, many investigations are performed to find new drugs for AD and medicinal plants are considered as one of the most important sources for developing new drugs. According to the role of oxidant agents and acetylcholinesterase enzyme (AChE) in AD, plants with antioxidant and AChE inhibitio...

Background: Ciprofloxacin was shown to have cytotoxic effects on testicular germ cells. Its mechanism of cytotoxic action is not fully understood. To investigate the possibility of the involvement of an oxidative stress induction in this mechanism, total antioxidant power (TAOP) in the testis was evaluated. Materials and Methods: A number of twenty four mature male NMRI mice were used.The anima...

OBJECTIVE To investigate the antihyperlipidemic, antioxidant, and cytotoxic effect of aqueous and methanol extract of leaves of Polygonum minus. MATERIALS AND METHODS Acute antihyperlipidemic effect was studied on chemically induced hyperlipidemic rat model. Treated groups received aqueous and methanol extract of leaves of P. minus respectively (1000 mg/kg; oral) whereas standard treated grou...