نتایج جستجو برای: transglutaminases

تعداد نتایج: 1752  

Journal: :Medical hypotheses 2015
Pål Stenberg Bodil Roth

UNLABELLED Post-translational modifications of proteins can generate antigenic conformations that may cause autoimmune diseases in persons with specific HLA-haplotypes. Monocytes and macrophages, attracted to an inflamed site, can release post-translationally acting enzymes, such as transglutaminases and peptidylarginine deiminases. In vivo, the activation of these enzymes is crucial for the fu...

2012
Agne Liedén Mårten C. G. Winge Annika Sääf Ingrid Kockum Elisabeth Ekelund Elke Rodriguez Regina Fölster-Holst Andre Franke Thomas Illig Maria Tengvall-Linder Hansjörg Baurecht Stephan Weidinger Carl-Fredrik Wahlgren Magnus Nordenskjöld Maria Bradley

BACKGROUND Atopic dermatitis (AD) is a common chronic inflammatory skin disorder where epidermal barrier dysfunction is a major factor in the pathogenesis. The identification of AD susceptibility genes related to barrier dysfunction is therefore of importance. The epidermal transglutaminases (TGM1, TGM3 and TGM5) encodes essential cross-linking enzymes in the epidermis. OBJECTIVE To determine...

Journal: :Journal of Biological Chemistry 1973

Journal: :Endoscopy 2006
F Torroni P De Angelis T Caldaro G Federici A Pane C Romano L Dall'oglio

We report here the case of a 15−year−old patient with symptoms characteristic of intestinal bleeding and severe anemia, who required repeated transfusions. The hematochemical parameters (erythrocyte sedimentation rate, CRP (c−reactive pro− tein), antineutrophil cytoplasmic antibo− dies, anti−Saccharomyces cerevisiae anti− bodies (ASCA), antiendomysium antibo− dies, and the transglutaminases), a...

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