The goal of the present case report is to enhance recognition of the incidence of tissue calcifications, which are quite common in patients with end-stage renal disease. We focus on pulmonary metastatic calcifications and the potential progression of this condition to tissue necrosis and lung cavitations in the setting of severe electrolyte imbalance. This case highlights the importance of earl...

We present a case of infantile-onset Alexander disease (AD) with a novel glial fibrillary acidic protein mutation but without clinical evidence of neurologic deterioration. Brain MRI studies showed typical AD findings and increasing size of frontal cavitations. Serial proton MR spectroscopy demonstrated high levels of myo-inositol and lactic acid and decreasing levels of N-acetylaspartate. The ...

The radiographic patterns of 23/33 (69.7%) Suruí indians, of the Brazilian Amazon, treated in 2003-2004 were analyzed. The analysis showed that 44.8% presented unspecific infiltrates, 10.3% presented cavitations and 39.1% presented multiple parenchymal involvements. Although 36% of the patients presented normal radiographs, they underwent anti-tuberculous treatment without having been submitted...

A 40-year-old female with metastatic breast cancer developed multiple lung nodules some of them with cavitations. Following treatment with Taxol/Herceptin most of the lesions disappeared and in many cavity lesions appeared. There was no further change in the appearance of lung lesions.

Adherence of blastoconidia to epidermal corneocytes is an early event in Candida colonization and infection of the skin. Pathogenic species adhere more avidly than nonpathogenic species, transform to hyphal growth, and invade the stratum corneum of the skin. Adherence was studied by scanning electron microscopy of experimental murine cutaneous Candida infections, using six species of Candida. C...

In tuberculosis endemic areas, patients with sputum positive for acid-fast bacilli (AFB) are usually diagnosed and treated for pulmonary tuberculosis. The diagnosis of nontuberculous mycobacteria (NTM) lung disease is often ascertained only after lung disease progression occurs, increasing the risk of severe morbidity and mortality. We conducted a matched case-control study among a prospective ...