iranian cave barb (iranocypris typhlops, bruun and kaiser, 1944)is one of thevery rareandendemicspeciesof iran. its distributionrangeislimitedina habitat that causes some problems for its conservation. thisuniquehabitatfaces somenatural and humanthreatsand the habitatdestructionmeansthe extinctionof the species. based on, habitat selection for translocation of the species is an important object...

Diphtheria toxin B fragment is capable of forming cation-selective channels in the plasma membrane. Such channels may be involved in the translocation of the toxin A fragment to the cytosol. Seven negatively charged amino acids in the B fragment were replaced one by one by lysines, followed by studies of cytotoxicity and channel-forming ability of the different mutants. The mutant D392K showed ...

Webster, Cynthia R. L., and M. Sawkat Anwer. Role of the PI3K/PKB signaling pathway in cAMP-mediated translocation of rat liver Ntcp. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G1165–G1172, 1999.—cAMP stimulates Na1-taurocholate (TC) cotransport by translocating the Na1TC-cotransporting peptide (Ntcp) to the plasma membrane. The present study was undertaken to determine whether the ...

background: acute lymphoblastic leukemia (all) is the most common subtype of childhood cancer. chromosomal ab­normality, specially the replacement of chromosomal material is one of the main reasons in generating leukemia, wherein the kind of translocation play a key role in managing the remedy. the goal of the present study was to develop a reliable, rapid, and cost effective method to detect t...

In the cell, nascent and completed polypeptides may misfold and aggregate. A class of proteins called molecular chaperones has evolved to facilitate the production of native, functional forms of proteins. These chaperones also aid in the translocation of proteins across biological membranes. The ubiquitous heat-shock protein (Hsp) 70 class of chaperones has been the subject of intensive study o...

a cytogenetic study was performed on 11 tetraploid cotton cultivars (gossypium hirsutum l.)including the oltan cultivar and its crossing progenies. the chromosome pairing and chiasma frequency, aswell as meiotic abnormalities were compared among the genotypes studied. heterozygote translocations withalternate orientation were observed between some of the chromosomes of the a genome and those of...

this paper provides information on the geographic distributions of two cyprinid species: hemiculter leucisculus (basilewsky, 1855) and alburnus caeruleus heckel, 1843, in the world and the entire drainage systems in iran. the new distribution records were taken from maroon river (jarrahi river system) and chardaval river (karkheh river system), both in tigris river basin showing wide and narrow...

abstract chromosomal translocations constitute one of the most important, yet uncommon, causes of primary amenorrhea and gonadal dysgenesis. although x-autosome translocations are frequently associated with streak gonads and clinical features of the turner syndrome, the majority of x-autosome carriers may present with a variable phenotype, developmental delay, and recognizable x-linked syndrome...

Results Elimination of Ca permeation through TRPC3 abrogated its ability to trigger NFAT translocation in both HEK293 cells and in HL-1 atrial myocytes. Wild-type TRPC3 was found capable of initiating NFAT translocation in atrial myocytes by a small, homogenous elevation of cytoplasmic Ca that was independent of voltagegated CaV1.2 channels. By contrast, a Ca 2+ impermeant TRPC3 mutant strongly...