traumatic brain injury is a leading cause of death in developed countries. it is estimated that only in the united states about 100,000 people die annually in parallel among the survivors there is a significant number of people with disabilities with significant costs for the health system. it has been determined that after moderate and severe traumatic injury, brain parenchyma is affected by m...

the incidence of traumatic brain injury (tbi) are annually increasing, developed tissue engineering methods could represent the definite remedies for patients with strongly injured central nervous system and have a great effect in the public healthcare cost. the current clinical treatments in tbi display several limitations. furthermore, several therapies, coming from neural tissue engineering ...

the sex hormone progesterone has been shown to improve outcomes in animal models and two early-phase trials involving patients with traumatic brain injury (tbi). the aim of this clinical study was to assess the effect of progesterone on the improvement of neurologic outcome in patients with diffuse and acute tbi. a prospective, randomized, double-blind trial of progesterone was conducted in our...

traumatic brain injury (tbi) is one the most common cause of disability between young adults. these people have been socially isolated during post-surgery traumatic brain injury. in this study we investigated the effect of social isolation on the structural deficits after tbi in the young rats. young rats were divided into control group with social interaction, sham group with social isolation ...

traumatic brain injury (tbi) results from a sudden and external physical impact to the head, and often leads to motor and cognitive impairment. using tissue engineering strategies, we aimed to review aspects of extra cellular matrix (ecm) based scaffold that could be delivered to the injured brain. the ecm is produced intracellularly and secreted to form a dense network of proteins and glycans,...

catatonia is a syndrome that can be treated with electroconvulsive therapy (ect). hence, onset of catatonia during treatment of patients with ect is not expected. in this manuscript, a schizoaffective disorder patient with a positive history of traumatic brain injury and no consumption of benzodiazepines is being reported, who became catatonic during ect.

Acute traumatic brain injury is a worldwide public health crisis. Post-traumatic subarachnoid hemorrhage (SAH) is a finding that is present at a frequency of 40% according to data from American TCDB (1,2). Among the mechanisms that have been implicated as causes of post-traumatic SAH is the cortical bleeding through the subarachnoid space. It is estimated that the incidence of post-traumatic SA...

war is an effective factor in incidence and promotion of psychological and behavioral problems such as post-traumatic stress disorder. this study aimed to determine the quality of life and its correlation with age and percent of injury in war veterans with post-traumatic stress disorder. this was a cross-sectional study, which included 70 war veterans with post-traumatic stress disorder. this s...

background & aim: traumatic brain injury is one of the main causes of death and disability. the aim of this study is to systematically review the articles which assessed some serum factors of traumatic brain injury patients in relation to their outcomes. methods & materials/patients: databases were searched for relevant publications from 2005 to 2014. selection criteria were:studies which evalu...