نتایج جستجو برای: trefoil factor family

تعداد نتایج: 1216883  

Journal: :American journal of respiratory and critical care medicine 1999
A Wiede W Jagla T Welte T Köhnlein H Busk W Hoffmann

Trefoil factor family (TFF)-domain peptides (formerly P-domain peptides, trefoil factors) represent major mucin-associated peptides of the gastrointestinal tract. Here, the first localization studies on TFF3 in the lower respiratory tract of human material are presented. Immunohistochemistry revealed significant accumulation of TFF3 to mucous cells in the acini of submucosal glands and varying ...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2013
Trevelyan R Menheniott Bayzar Kurklu Andrew S Giraud

During the past decade, a new family of stomach-specific proteins has been recognized. Known as "gastrokines" (GKNs), these secreted proteins are products of gastric mucus-producing cell lineages. GKNs are highly conserved in physical structure, and emerging data point to convergent functions in the modulation of gastric mucosal homeostasis and inflammation. While GKNs are highly prevalent in t...

Journal: :Endocrine journal 2009
Toru Takano Hiroya Yamada

Since the introduction of fine needle aspiration biopsy (FNAB) in the 1970's, a preoperative diagnostic technique for thyroid follicular carcinoma has long been awaited. Many markers that distinguish follicular carcinomas from adenomas have been reported; however, most of them have not been confirmed to be beneficial for clinical use. Trefoil factor 3 (TFF3) is a relatively new family of peptid...

Journal: :Journal of molecular biology 1997
V I Polshakov M A Williams A R Gargaro T A Frenkiel B R Westley M P Chadwick F E May J Feeney

pNR-2/pS2 is a 60 residue extracellular protein, which was originally discovered in human breast cancer cells, and subsequently found in other tumours and normal gastric epithelial cells. We have determined the three-dimensional solution structure of a C58S mutant of human pNR-2/pS2 using 639 distance and 137 torsion angle constraints obtained from analysis of multidimensional NMR spectra. A se...

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