Subgroup discovery aims at constructing symbolic rules that describe statistically interesting subsets of instances with a chosen property of interest. Semantic subgroup discovery extends standard subgroup discovery approaches by exploiting ontological concepts in rule construction. Compared to previously developed semantic data mining systems SDM-SEGS and SDM-Aleph, this paper presents a gener...

We previously demonstrated that prodynorphin (PDYN) haplotypes and single nucleotide polymorphism (SNP) rs2281285 are associated with alcohol dependence and the propensity to drink in negative emotional states, and recent studies suggest that PDYN gene effects on substance dependence risk may be sex-related. We examined sex-dependent associations of PDYN variation with alcohol dependence and re...

personalized medicine aims is to supply the proper drug to the proper patient within the right dose. pharmacogenomics (pgx) is to recognize genetic variants that may influence drug efficacy and toxicity. all things considered, the fields cover a wide area, including basic drug discovery researches, the genetic origin of pharmacokinetics and pharmacodynamics, novel drug improvement, patient gene...

BACKGROUND Sensors detect the rate and direction of glucose trend. They need to be accurate and reproducible as could be evidenced by strong agreement between multiple sensors. We evaluated this relationship through simultaneously worn glucose sensors using several methods of slope analysis. METHODS Ten type 1 diabetic, insulin pump-treated subjects were studied while simultaneously wearing t...

The trend that the electronic market is taking, aided by the concomitant development of mobile devices, suggests a major change from the way electronic commerce is done today. The increased use of PDAs and laptops requires that ecommerce services and transaction processing facilities need to be accessed from a wireless device. This brings new and challenging research problems into the picture. ...

In ubiquitous computing environments to use distributed services and devices efficiently the basic information should be provided about types or locations of services in advance. A process explores such information that meets a user's needs. We call it as service discovery which is the most primitive system in distributed mobile computing environment such as ubiquitous. It is a trend that use o...

Service discovery is one of the crucial issues for service-oriented architectural model. Recently the trend is towards semantic discovery by which semantic descriptions are the basis for service matchmaking instead of simple search based on service attributes. OWL-S is a widely adopted semantic specification for Web Services which comprises three profiles. Among those, process model is the prof...

decision support systems (dsss) are prevalent information systems for decision making in many competitive business environments. in a dss, decision making process is intimately related to some factors which determine the quality of information systems and their related products. traditional approaches to data analysis usually cannot be implemented in sophisticated companies, where managers need...

decision support systems (dsss) are prevalent information systems for decision making in many competitive business environments. in a dss, decision making process is intimately related to some factors which determine the quality of information systems and their related products. traditional approaches to data analysis usually cannot be implemented in sophisticated companies, where managers nee...

ontology is a requirement engineering product and the key to knowledge discovery. it includes the terminology to describe a set of facts, assumptions, and relations with which the detailed meanings of vocabularies among communities can be determined. this is a qualitative content analysis research. this study has made use of ontology for the first time to discover the knowledge of vaccine in ir...