Bone marrow aspiration (BMA) and bone marrow trephine biopsy are important procedures for the diagnosis of hematological malignancies and nonmalignant diseases in children. During BMA, bone marrow particles are obtained for analysis including microscopic morphologic evaluations and differential counts. During a trephine biopsy, a core of bone marrow is obtained and processed for the evaluation ...

INTRODUCTION In Non-Hodgkin Lymphoma (NHL), bone marrow histology is the gold standard against which ancillary investigations such as immunophenotyping and gene rearrangement studies are interpreted. There is currently no data on the reproducibility of histological findings. This study was conducted to determine the rates of inter- and intra-observer agreement in histological detection of bone ...

Two hundred and eight serial bone marrow samples from 49 consecutively diagnosed children with neuroblastoma were studied retrospectively for evidence of tumour invasion. Bone marrow involvement was found in 24 patients at diagnosis and in four more at a later stage in their disease. Trephine biopsies were more effective than aspirates for tumour detection in 20% of the 154 paired aspirate/trep...

Introduction Marrow biopsy by surgical trephine is an older procedure than needle aspiration. It is only since the late 1950s that core needle biopsy of the bone marrow has been widely used. Since that time, it has had a considerable effect on diagnostic haematology, pathology and oncology. Wide acceptance is associated with the introduction of a simple procedure using the Jamshidi needle to im...

Introduction Examination of bone marrow biopsy specimens is a valuable diagnostic procedure in patients with known or suspected lymphoproliferative disorders. ' A bone marrow biopsy specimen may be diagnostic in patients without lymphadenopathy or when there is no conclusive histological evidence from other sites. In some conditions, such as hairy cell leukaemia,2 it is the primary diagnostic p...

Multiple myeloma is a malignant proliferation of plasma cells that typically presents in the bone marrow.Extramedullaryplasmacytoma (EMP) represents an unusual and characteristically progressive malignancythat can arise outside marrow. The occurrence multiple with plasmacytoma thelung very unusual. Herein, we report case lungdiagnosed by CT-guided FNAC marrow trephine biopsy. J MEDICINE 2022; 2...

Needle lung biopsy performed with a trephine cutting needle attached to a high speed pneumatic drill is a new technique which can be expected to yield a high quality lung specimen in 85 percent 90 percent of attempts. This technique is especially applicable to diffuse pulmonary disease. The most frequent complication is the development of pneumothorax (in up to 65 percent of biopsies) which if ...