the synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzo thieno[2,3-d]pyrimidin-3(4h)-amine 3 has been developed in 3 steps through the reaction of heteroaromatic o-aminonitrile 1 with triethyl orthoformate afforded the corresponding imido ester 2 followed by cyclization with hydrazine hydrate to furnish iminothienopyrimidineamine 3 and finally the imination ...

The title compound, [RuCl(C(6)H(7)N)(2)(C(27)H(35)N(3))]PF(6)·C(3)H(6)O, was obtained unintentionally as the product of the reaction of 1,1'-methyl-enebis(4-methyl-pyridinium) hexa-fluoriso-phos-phate and RuCl(3)(tpy*) (tpy* is 4,4',4''-tri-tert-butyl-2,2':6',2''-terpyridine) in the presence of triethyl-amine and LiCl. The mol-ecular structure of the complex displays an octa-hedral geometry aro...

The reaction of diethyl phosphite with triethyl orthoformate and a primary amine followed by hydrolysis is presented, and the reaction was suitable for the preparation of (aminomethylene)bisphosphonates. 3-Amino-1,2,4-triazole was chosen as an interesting substrate for this reaction because it possesses multiple groups that can serve as the amino component in the reaction-namely, the side-chain...

An isocratic reversed phase high-performance liquid chromatographic method with ultraviolet detection at 220 nm has been developed for the quantification of itopride hydrochloride in tablet dosage form. The quantification was carried out using C(8) column (250 mm × 4.6 mm), 5-μm particle size SS column. The mobile phase comprised of two solvents (Solvent A: buffer 1.4 mL ortho-phosphoric acid a...

In the present study a simple, accurate & precise reverse phase liquid chromatographic method has been developed & validated for simultaneous estimation of Atenolol & Indapamide from tablet dosage form. The method was developed using Waters HPLC system on a L1 column (Hypersil Gold: 250mm x 4.6 mm, 5μm) using a mixture of 0.1% Triethyl Amine in water of pH 3.0 & Methanol in the ratio 30:70 v/v ...

The synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzo thieno[2,3-d]pyrimidin-3(4H)-amine 3 has been developed in 3 steps through the reaction of heteroaromatic o-aminonitrile 1 with triethyl orthoformate afforded the corresponding imido ester 2 followed by cyclization with hydrazine hydrate to furnish iminothienopyrimidineamine 3 and finally the imination ...

A stability indicating reversed phase HPLC assay method has been used for the simultaneous assay of piracetam and cinnarizine drugs in hard gelatin capsule formulation. The separation is achieved by gradient elution using Hypersil BDS C8 column (250 mm × 4.6 mm, i.d. 5 μm particle size) with mobile phase (A) consisting of 0.015 M dipottassium hydrogen phosphate and 2 mL of triethyl amine adjust...

SINGLE CRYSTALS OF THE NEW TITLE COMPOUND [SYSTEMATIC NAME: 1,4,7,10-tetra-zoniadecane hexa-chloridorhodate(III) chloride], [H(3)N(CH(2))(2)NH(2)(CH(2))(2)NH(2)(CH(2))(2)NH(3)][RhCl(6)]Cl, were obtained from the corresponding amine and rhodium trichloride in hydro-chloric acid solution by slow crystallization under diffusion-controlled conditions at room temperature. Its solid-state structure i...