The objective of the study was to search for the appropriate herbal extracts by comparative analysis of their estrogenic and cytotoxic activities. Some potentially estrogenic activity of herbal extracts in the management of female disorder symptoms was investigated by E-screen assay. The extracts having a promising activity were further evaluated in vitro for their cytotoxic activity. Of 13 her...

Background: The main goals of our study were as follows: (1) to investigate whether the methanolic extract of the new cultivar (Gürarslan) of Trigonella foenum graecum L. seeds exhibit antiproliferative effects on the HeLa human cervix carcinoma, Mat-LyLu rat prostate carcinoma and 3T3 embryonic mouse fibroblast cell lines, (2) to determine how mitosis and DNA synthesis are affected in cancer c...

The aim of the study was to evaluate the effect of Trigonella foenum-graecum (fenugreek) seed extract on sex hormones and sexual function in healthy menstruating women who reported low sexual drive. This short term, single site, double blind, randomised, placebo-controlled study was conducted on 80 women, aged 20 to 49 years. Participants were randomised to either an oral dose of a standardised...

Oxidative stress is currently suggested to play a major role in the development of diabetes mellitus. There is an increasing demand of natural anti-diabetic agents, as continuous administration of existing drugs and insulin are associated with many side effects and toxicity. The present study was aimed to investigate the effect of Momordica charantia (MC) and Trigonella foenum graecum (TFG) ext...

The objective of the present study was to evaluate the phytochemical constitution and antioxidant activity of methanolic extract of dried leaves of four medicinally important herbs Ocimum sanctum, Mentha spicata, Trigonella foenum-graecum, Spinacia oleracea utilized in our routine diet along with one medicinal important tree Gmelina arborea. Qualitative analysis of phytochemical constituents’ v...

BACKGROUND Trigonella foenum-graecum (L.) (Fabaceae, Fenugreek) is an important ingredient of Ayurvedic and other marketed herbal formulations. Fenugreek seeds are employed in many traditional systems as an antibacterial and antidiabetic agent, gastric stimulant and galactogogue. Trigonelline, a major phytoconstituent found in fenugreek seeds, shows estrogenic, anti-diabetic and anti-invasive a...

to study the effect of salinity stress on seed germination and seedling growth of four medicinal plants, nigella sativa l., cannabis sativa l., trigonella foenum graecum and cynara scolymus l. an experiment was conducted in the botany laboratory of islamic azad university, birjand branch. a completely randomized design (crd) with 3 replications was used as separately for each species. treatment...

Comparative efficacy of two indigenous herbal extracts, (Trigonella foenum-graecum seed & Coccinia indica leaves) with the commonly used drug Glimepiride were studied. Healthy young rats (n=30) of both sexes weighting between 150 to 200 gm were selected and divided into six equal groups, as A (Control), B (diabetic), experimental diabetic groups wereC, D, E and F, treated with combined extract ...

fenugreek (trigonella foenum-graecum l.), wild or cultivated, is widely distributed throughout the world and belongs to the fabacecae family. it is an old medicinal plant and has been commonly used as a traditional food and medicine. fenugreek is known to have hypoglycemic, and hypocholesterolaemic, effects. recent research has identified fenugreek as a valuable medicinal plant with potential f...