نتایج جستجو برای: triple negative

تعداد نتایج: 572352  

2015
Zining Jin Wenqian Wang Nan Jiang Lei Zhang Yiming Li Xiaoyin Xu Shouliang Cai Liang Wei Xuhong Liu Guanglei Chen Yizhen Zhou Cheng Liu Zhan Li Feng Jin Bo Chen Ying-Jan Wang

Triple-negative breast cancer is a high-risk breast cancer with poor survival rate. To date, there is a lack of targeted therapy for this type of cancer. One unique phenomenon is that inflammatory breast cancer is frequently triple negative. However, it is still ambiguous how inflammation influences triple-negative breast cancer growth and responding to chemotherapy. Herein, we investigated the...

Journal: :The Annals of The Royal College of Surgeons of England 2020

2015
Pawel Domagala Anna Jakubowska Katarzyna Jaworska-Bieniek Katarzyna Kaczmarek Katarzyna Durda Agnieszka Kurlapska Cezary Cybulski Jan Lubinski Alvaro Galli

PURPOSE This study sought to assess the prevalence of common germline mutations in several genes engaged in the repair of DNA double-strand break by homologous recombination in patients with triple-negative breast cancers and hereditary non-triple-negative breast cancers. Tumors deficient in this type of DNA damage repair are known to be especially sensitive to DNA cross-linking agents (e.g., p...

Journal: :iranian journal of blood and cancer 0
safa najafi breast cancer research centre, acecr, tehran, iran hamid reza mozaffari department of oral medicine, school of dentistry, kermanshah university of medical sciences, kermanshah, iran; medical biology research center, kermanshah university of medical sciences, kermanshah, iran masoud sadeghi medical biology research center, kermanshah university of medical sciences, kermanshah, iran; student research committee, kermanshah university of medical sciences, kermanshah, iran

background: triple negative breast cancer (tnbc) is reported to be associated with a high risk of recurrence, poor overall survival (os), and disease-free survival (dfs) rates. this study evaluated the clincopathological features and survival of non-metastatic tnbc women in the capital of iran compared with other areas of the world. methods: in a retrospective study, 119 women with tnbc based o...

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