Background: Infertility is defined as 1 year of unprotected intercourse without pregnancy. The main causes of infertility are as follows: male factor, Both mail and female, as well as unexplained etiologies. Tubal and peritoneal factors Aceount for 30%-40% of causes of female infertility. Tubal factors include damage and obstraction of the fallopian tube, usually associated with previous pelvic...

Infertility is a worldwide health problem with one in six couples suffering from this condition and with a major economic burden on the global healthcare industry. Estimates of the current global infertility rate suggest that 15% of couples are infertile (ZegersHochschild et al., 2009) defined as: (1) failure to conceive after one year of unprotected sexual intercourse (i.e. infertility); (2) c...

INTRODUCTION Fallopian tube damage and subsequent infertility are common sequelae of upper genital tract infection with Chlamydia trachomatis. This fallopian tube damage is thought to be immune mediated. The 60 kilodalton chlamydial heat shock protein (hsp) may be the key antigen associated with this pathogenic response. Our objective was to study the relationship between antibody response to 6...

The main female anatomical causes of infertility include post-infectious tubal damage, endometriosis, and congenital/acquired uterine anomalies. Congenital (septate uterus) and acquired (myomas and synechiae) diseases of the uterus may lead to infertility, pregnancy loss, and other obstetric complications. Pelvic inflammatory disease represents the most common cause of tubal damage. Surgery sti...

Effectiveness of screening Chlamydia trachomatis (CT) antibody to predict tubal damage was assessed in this prospective study which was performed in a teaching hospital between September 2003 and September 2004. The study group consisted of 152 patients who underwent laparoscopy for infertility and the control group consisted of 80 fertile women who gave birth in the same hospital. CT antibody ...

OBJECTIVE To examine the effect of peritoneal fluid (PF) of patients with endometriosis on the cytoskeleton of metaphase II oocytes and correlate the results with the stage of endometriosis and the duration of infertility. DESIGN Prospective-controlled study. SETTING Center for reproductive medicine at a tertiary-care hospital. PATIENT(S) Women with endometriosis (n=23) and tubal ligation...

OBJECTIVE To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082,...

Ovarian cancer is the most lethal gynecological malignancy affecting American women. Current hypotheses concerning the etiology of ovarian cancer propose that a reduction in the lifetime number of ovulations decreases ovarian cancer risk. Advanced serous carcinoma shares several biomarkers with fallopian tube epithelial cells, suggesting that some forms of ovarian carcinoma may originate in the...

background: reversal of tubal ligation is requested by some women for various reasons. the present study aims to determine the rate of pregnancy after tubal ligation reversal. case: in these case series, we reported fifteen women who requested tuboplasty after tubal ligation. in these cases reversal of tubal ligation was done in 15 women. pregnancy occurred in 4 women (26.6%). two term pregnanc...

The tubal fimbria is a common site of origin for early (tubal intraepithelial carcinoma or TIC) serous carcinomas in women with familial BRCA1 or 2 mutations (BRCA+). Somatic p53 tumour suppressor gene mutations in these tumours suggest a pathogenesis involving DNA damage, p53 mutation, and progressive loss of cell cycle control. We recently identified foci of strong p53 immunostaining-termed '...