Information about the aggregation state of fine particles is an important element for process control, product quality monitoring and fundamental understanding in many cases of industrial slurries. W hen aggregates are small or fragile objects, their w ithdraw al is difficult and off-line characterization may be a source of error. This w ork deals w ith the application of different in line meth...

Absorption spectrophotometry is the measurement of an interaction between electromagnetic radiation and the molecules, or atoms, of a chemical substance. Techniques frequently employed in pharmaceutical analysis include UV, visible, IR, and atomic absorption spectroscopy. Spectrophotometric measurement in the visible region was formerly referred to as colorimetry; however, it is more precise to...

HE CHOICE OF RAPID METHODS for estimation of serum amylase activity is limited (1). Such methods depend upon the change in color of starch with iodine brought about by splitting of the starch by the enzyme. it is often difficult to establish an end point visually by this reaction in partially digested starch solutions, especially by those whose experience with the method is limited. Furthermore...

A sensitive latex immunoassay for human serum lipoprotein Lp(a+) is based on direct agglutination by Lp(a+) of latex particles coated with specific antibody. The agglutination is quantified by turbidimetry using a photometer at 360 nm. The stabilization of antibody-coated latex particles by bovine serum albumin occurs under well-defined conditions (pH, concentration of bovine serum albumin, and...

The objectives of the present work were, first, to develop a self-nanoemulsified drug delivery system (SNEDDS) based on the eutectic properties of ubiquinone (CoQ10); and second, to study the progress of emulsion formation and drug release mechanisms by turbidimetry and droplet size analysis. Binary phase diagrams of CoQ10 with menthol and essential oils were constructed and used to develop the...

Two simple, rapid and inexpensive methods based on spectrophotometry and turbidimetry have been developed for the determination of cyproheptadine hydrochloride (CPH) in pure form and in dosage forms with Bromophenol Blue (BPB) as the reagent. The spectrophotometric method is based on the formation of an ion-pair complex between the drug and BPB in an acidic buffer. The ion-pair complex formed, ...