Calcium mineral deposits are radiographically evident in the majority of significant atherosclerotic lesions.1 These deposits generally consist of a nonhomogeneous composite containing hydroxyapatite mineral nanocrystals embedded in an organic matrix including type I collagen nanofibers. The morphometry varies over a spectrum. Amorphous deposits lack organization at the lightmicroscopic scale, ...

Renal organized or structured deposits are much less frequent than those with usual type immunocomplex deposits and are encountered in a wide variety of primary and systemic disorders. It has been suggested that immunoglobulins (Igs) are responsible for organized deposits. We report 5 cases who have been diagnosed and treated in our hospital. Patients were aged 52 to 72 years, three of them wer...

The northern Asia, including the southern territories of Russia, Kazakhstan, Uzbekistan, Mongolia and the northern China is known as an important distribution region of uranium deposits and occurrences. Since the 60s of 20th century, after the successful development of in-situ leach technology for sandstone-hosted uranium deposits, numerous uranium deposits previously discovered in Kazakhstan a...

In this paper, we used 3D modeling and nonlinear methods (fractal, multifractal, and probabilistic neural networks (PNN)) for regional mineral potential mapping and quantitative assessment for porphyry and skarn-type Mo deposits and hydrothermal vein-type Pb–Zn–Ag deposits in the Luanchuan region, China. A 3D geological model was constructed from various geological maps, cross sections, borehol...

OBJECTIVE To establish the correlations among the mineral components, progressive calcification process and clinical symptoms of calcific tendonitis. METHODS The morphology of the calcified deposits on the shoulders of 28 patients with calcific tendonitis was determined by high-resolution ultrasonography. The calcified deposit from each patient was aspirated and determined by the Fourier tran...

Outbred Wistar rats immunized with native type II collagen developed ear lesions resembling those of human relapsing chondritis. As in human disease, these lesions were characterized by intense chondritis, positive immunofluorescence reactions to IgG and C3, and circulating IgG reactive with native type II collagen. Furthermore, electron-dense deposits were seen near the surface of chondrocytes...

INTRODUCTION Transgenic overexpression of amyloid precursor protein (APP) genes that are either entirely human in sequence or have humanized Aβ sequences can produce Alzheimer-type amyloidosis in mice, provided the transgenes also encode mutations linked to familial Alzheimer's Disease (FAD). Although transgenic mice have been produced that overexpress wild-type mouse APP, no mice have been gen...

In variant Creutzfeldt-Jakob disease (vCJD), a disease linked to bovine spongiform encephalopathy (BSE), florid-type prion protein (PrP(sc)) deposits are aggregated around the larger diameter (> 10 µm) cerebral microvessels. Clustering of PrP(sc) deposits around blood vessels may result from blood-borne prions or be a consequence of the cerebral vasculature influencing the development of the fl...