introduction: sonophoresis has been assessed as a novel approach to create skin permeability and drug delivery using low frequencies of ultrasound waves in the range of 20 khz to 3 mhz. in this study, a system including seven 40 khz piezoelectric transducers and an insulin chamber designed by the medical physics research center has been evaluated on hyperglycemic rabbits. materials and methods:...

In this investigation a simple synthetic method for the synthesis of trifluoromethyl-1H-benzo[e][1,2,4]triazolo[1,2-a][1,2,4]triazine-1,3(2H)-diones and (trifluoromethyl)benzo [5,6][1,2,4]triazino[1,2-b]phthalazine-8,13-diones has been developed using urazole or phthalazine and aceteimidoyl chloride derivatives at room temperature under ultrasound irradiations. In the comparison to the conventi...

background: drug nano-carriers are one of the most important tools for targeted cancer therapy so that undesired side effects of chemotherapy drugs are minimized. in this area, the use of ultrasound can be helpful in controlling drug release from nanoparticles to achieve higher treatment efficiency. objective: here, we studies the effects of ultrasound irradiation on the release profile of 5-fl...

Understanding of cell death caused by ultrasonic exposure is important factor in the field of ultrasound diagnosis and clinical trial[1]. Biological cell death is classified with three type: apoptotic cell death or programmed cell death, necrotic cell death and autophagic cell death. Each death form is defined as a morphological structure and specific death pathway. Recently, it was reported ul...

Objective: This study aimed to explore ultrasound-guided injections of Ultrasound Contrast Agents (UCAs) and p53 gene for the treatment of rats with breast cancer. Methods: With the construction of p53 expression vector and rat model with breast cancer, 160 rats that modeled successfully were randomly divided into 4 groups: p53 gene introduction group, p53 gene introduction+ultrasound irradiati...

The degradation of poly (vinyl pyrrolidone) (PVP) by means of ultrasound irradiation and itscombination with heterogenous photocatalysis (TiO2 nanoparticles) was investigated. Emphasiswas given on the effect of additive on degradation rate constants. 24 kHz of ultrasoundirradiation was provided by a sonicator, while an ultraviolet source of 30 W was used for UVirradiation. To increase the effic...

An ultrasound-assisted extraction (UAE) method was developed for the efficient extraction of natural antioxidants from the flowers of Jatropha integerrima. Four independent variables, including ethanol concentration, solvent/material ratio, ultrasound irradiation time and temperature were studied by single factor experiments. Then, the central composite rotatable design and response surface met...

AIMS AND BACKGROUND The cellular response of hepatoma-22 cells to ultrasonic irradiation and the potential cause for the action were evaluated. METHODS AND STUDY DESIGN Hepatoma-22 cells were subjected to ultrasound irradiation at a frequency of 2.17 MHz and a spatial average intensity of 1.6 W/cm2 for variable periods of time, and several biological parameters were analyzed. The terephthalic...