how to cite this article: ghofrani m. approach to the first unprovoked seizure- part ii. iran j child neurol. 2013 autumn; 7(4):1-5. abstract the approach to a child who has experienced a first unprovoked generalized tonic-clonic seizure is challenging and at the same time controversial. how to establish the diagnosis, ways and means of investigation and whether treatment is appropriate, are di...

BACKGROUND Approximately 7-10% of patients with unprovoked VTE will be diagnosed with cancer within 12 months. Although cancer screening has been proposed in these patients, the optimal strategy remains unclear. In a pilot study, we prospectively investigated the use of FDG-PET/CT to screen for occult malignancy in 40 patients with unprovoked VTE. MATERIALS/METHODS Patients were initially scr...

Synopsis Patients with unprovoked VTE have a higher risk of recurrence than those with a provoked event. This is the first study to evaluate extended anticoagulation beyond six months for patients with unprovoked PE. The authors enrolled adults (N = 371), 18 years or older, who received six months of therapy with a vitamin K antagonist following their first episode of symptomatic unprovoked PE....

Objectives This is a protocol for Cochrane Review (prognosis). The objectives are as follows: Primary To identify which prognostic factors predict whether individuals will go on to have further unprovoked seizures and the development of epilepsy at any subsequent time point following single seizure (or cluster epileptic within 24‐hour period, or first episode status epilepticus), type. Investig...

BACKGROUND It is unclear how frequently unprovoked venous thromboembolism (VTE) reflects the presence of an occult cancer. METHODS The California Cancer Registry was used to identify diagnosed cases of 19 common malignancies during a 6-year period. Cases were linked to a hospital discharge database to identify incident VTE events in the year before the cancer diagnosis date. The standardized ...

PURPOSE To synthesize evidence concerning the effect of antiepileptic drugs (AEDs) for seizure prevention and to contrast their effectiveness for provoked versus unprovoked seizures. METHODS Medline, Embase, and The Cochrane Clinical Trials Register were the primary sources of trials, but all trials found were included. Minimal requirements: seizure-prevention outcome given as fraction of cas...

Abstract Russia’s unprovoked and unjustified full-scale invasion of Ukraine has significantly changed the geopolitical circumstances on European continent is also importantly reshaping EU’s enlargement policy.

BACKGROUND Patients who have had an unprovoked deep venous thrombosis (DVT) or pulmonary embolus (PE) are at a high risk for recurrent venous thromboembolism (VTE). Extended "life-long" anticoagulation has been recommended in these patients. However, the risk benefit ratio of this approach is controversial and the role of the direct oral anticoagulants (DOACs) and aspirin is unclear. Furthermor...

BACKGROUND Venous thromboembolism (VTE) is a collective term for two conditions: deep vein thrombosis (DVT) and pulmonary embolism (PE). A proportion of patients with VTE have no underlying or immediately predisposing risk factors and the VTE is referred to as unprovoked. Unprovoked VTE can often be the first clinical manifestation of an underlying malignancy. This has raised the question of wh...