INTRODUCTION One of the most common complaints in patients with end-stage renal disease (ESRD) is uremic pruritus. In the recent years, many drugs have been proposed for its treatment which have had paradoxical outcomes. We studied the antipruritus effect of montelukast sodium, a leukotriene receptor antagonist, in patients on hemodialysis. MATERIALS AND METHODS The study was conducted as ran...

OBJECTIVE To document various characteristics of uremic pruritus in patients undergoing haemodialysis. DESIGN Case series. PLACE AND DURATION OF STUDY This study was carried out at Sindh Institute of Urology, Karachi, and Departments of Dermatology and Medicine, PNS Shifa, Karachi, over a period of 3 months. PATIENTS AND METHODS One hundred patients of end stage renal disease undergoing h...

We report a unique observation characterized by the coexistence of idiopathic adulthood ductopenia (IAD), a rare cholestatic disease, and end stage renal failure treated by conventional hemodialysis in a patient awaiting double renal and liver transplantation. As pruritus gradually worsened, we hypothesized that intensified dialysis could alleviate the symptoms. Conventional hemodialysis follow...

Uremic pruritus is a very common and frustrating condition for both patients and clinicians because no treatment has been demonstrated to be effective in relieving the itch. In this report, nalfurafine, a new kappa-opioid receptor agonist, was used to treat uremic pruritus in patients who were undergoing routine hemodialysis. Two multicenter, randomized, double-blind, placebo-controlled studies...

Aim: This study was conducted in order to determine the dermatological and kidney disease quality of life patients with uremic pruritus receiving hemodialysis treatment. Material Methods: The present a descriptive study. sample comprised 200 HD patients. participants were required complete patient information form, 5-D-Itch scale, Dermatological Quality Life Index (DLQI) Kidney Disease Form (KD...