Urinary tract infection (UTI) is one of the most common bacterial infections in humans, with uropathogenic Escherichia coli (UPEC) the leading causative organism. UPEC has a number of virulence factors that enable it to overcome host defenses within the urinary tract and establish infection. The O antigen and the capsular polysaccharide are two such factors that provide a survival advantage to ...

A 64-year-old man with a prostate-specific antigen (PSA) of 5·74 ng/mL, no lower urinary symptoms, and family history prostate cancer presented at our clinic University College London Hospital (London, UK) in April, 2018. Axial T2-weighted MRI the showed multicystic lesion (PSA density 0·07 ng/mL/mL), MRI-targeted biopsies Gleason 3 + adenocarcinoma (Gleason Grade Group 1) prostatic intraepithe...

The main aim of our study was to determine the added value of PCR for the diagnosis of Legionnaires' disease (LD) in routine clinical practice. The specimens were samples submitted for routine diagnosis of pneumonia from December 2002 to November 2005. Patients were evaluated if, in addition to PCR, the results of at least one of the following diagnostic tests were available: (i) culture for Le...

in addition to ultrasonographic monitoring of folliculogenesis, urinary luteinizing hormone testing, luteal phase endometrial biopsy, serum antiphospholipid antibodies, etc., immunologic tests are recently being used to evaluate reproductive disorders. in this study, sharing of hla-a, b, c and dr antigens and the presence of antipaternal cytotoxic antibody (apca) was assessed using microcytotox...

The article of Robert F. Benson et al. entitled “Evaluation of the Binax and Biotest urinary antigen kits for detection of Legionnaires’ disease due to multiple serogroups and species of Legionella” (1) states the following in the abstract: “Eighteen were positive with the Binax kit, and 13 were positive with the Biotest.” This statement is misleading since data in both the article and Table 1 ...

We evaluated the Binax NOW Streptococcus pneumoniae urinary antigen assay by testing 210 healthy children aged 2--60 months living in urban slums of Quito, Ecuador. Healthy children with nasopharyngeal carriage of S. pneumoniae were significantly more likely to have positive urinary antigen test results than were children who were not carriers (30 of 138 vs. 3 of 71 children; chi2=10.8; P<.001)...

In 1990-2002, the authors conducted a population-based cohort study of 2,447 Caucasian men in Olmsted County, Minnesota, to determine whether daily users of nonsteroidal antiinflammatory drugs (NSAIDs) were at lower risk than nondaily NSAID users of developing benign prostatic hyperplasia. Participants completed validated questionnaires during a home visit, including information about daily NSA...

The pneumocococcal urine antigen test increases specific microbiological diagnosis over conventional culture methods in pneumonia patients. Data are limited regarding its yield and effect on antibiotic prescribing among patients with community-onset pneumonia in clinical practice. We performed a secondary analysis of 2837 emergency department patients admitted to seven Utah hospitals over 2 yea...