background: psychological and behavioral domains are important in coping with type ii diabetes. this study was conducted to assess supportive and coping obstacles in living with type ii diabetes among patients who visited hospitals affiliated to tehran university of medical sciences (tums). methods: this was a cross-sectional study with 600 subjects who participated in the study. data collectio...

BACKGROUND/AIMS Acute tubular necrosis (ATN), a leading cause of acute kidney injury (AKI), is associated with decreased survival and increased progression of chronic kidney disease. A barrier to improving the clinical outcomes is the incomplete understanding of the pathogenesis of AKI. Our objective is to test the hypothesis that intrarenal renin-angiotensin system (RAS) is overexpressed in pa...

BACKGROUND Although autistic spectrum disorders (ASD) are a strongly genetic condition certain metabolic disturbances may contribute to clinical features. Metabolism of oxalate in children with ASD has not yet been studied. AIM The objective was to determine oxalate levels in plasma and urine in autistic children in relation to other urinary parameters. METHOD In this cross-sectional study,...

OBJECTIVE Reactive oxygen species (ROS) play a role in cancerogenesis processing and damage tissues. Furthermore, oncological treatment may impair proper function of the gut barrier. The aim of this study was to measure intestinal permeability in children in clinical remission for solid tumours and to search for a possible relationship between free radicals and the intestinal barrier. No such i...

conclusions urinary ghrelin concentration was lower before treatment of uti and significantly increased after cessation of inflammation. further studies are required for more definite results. patients and methods this study was performed on 40 hospitalized children with uti at mofid children’s hospital during years 2013 to 2014. ghrelin and creatinine were measured before and after treatment. ...

BACKGROUND Most older adults with urinary incontinence use absorbent pads. Because of exposure to moisture and chemical irritating substances in urine, the perineal skin region is always at risk for development of incontinence-associated dermatitis (IAD). The aim of this study was to examine the efficacy of an improved absorbent pad against IAD. METHODS A cluster randomized controlled design ...

Macrophages have been postulated to play an important role in the pathogenesis of HIV-1 infection. Their ability to cross the blood-brain barrier and their resistance to virus-induced cytopathic effects allows them to serve as reservoirs for long-term infection. Thus, exploring the mechanisms of virus transmission from macrophages to target cells such as other macrophages or T lymphocytes is ce...

The eosinophil granule protein major basic protein (MBP) is toxic to a wide variety of cell types, by a poorly understood mechanism. To determine whether the action of MBP involves an alteration in membrane permeability, we tested purified MBP on rabbit urinary bladder epithelium using transepithelial voltage-clamp techniques. Addition of nanomolar concentrations of MBP to the mucosal solution ...

introduction: aim was to study the influence of serum testosterone and urinary citrate on the formation of urinary stones in men and women, and to apply the findings for preventing urolithiasis. methods: we studied 200 patients (100 were men and 100 women) who had referred to the urology clinic at imam khomeini hospital and seda sima eswl center. in both groups, 50 were stone formers and 50 wer...

conclusions the influences of various facilities and barriers were different in the physical activity of elderly in kashan. the promotion of active life style should be a part of health care planning in elderly. background the supplements and decreasing the limitations are important for suitable physical activity. these factors are different in various environments. objectives the current study...