• AOS and GOS decreased the E. coli growth by different concentrations. AOS-Ampicillin exerted 2-fold decrease in MIC level of AMP against . reduced adherence to HT-29 cells. The combination further increased AOS’ anti-adhesive properties. AOS, COS or significantly hampered -induced IL-8 release HT-29. mounting antibiotic resistance emphasizes an urgent need for alternatives. Recent investigati...

s: Several oligosaccharides such as glycosylsucrose, fructo-oligosaccharides, maltooligosaccharides, isomalto-oligosaccharides (branched-oligosaccharides), galacto-oligosaccharides, xylo-oligosaccharides, isomaltulose (palatinose), and lactosucrose have been produced on an industrial scale. Recent developments in industrial enzymology have made possible a series of new starch oligosaccharides s...

Abstract Polygonatum sibiricum, famous for its physiological activities, is a popular Chinese food and also traditional herb containing many carbohydrates as the main component. However, except most reported polysaccharides, other detailed compositions of were still not clear. To verify controversial existence starch investigate components especially about oligosaccharides, we used iodine-potas...

BACKGROUND Extraintestinal pathogenic E. coli are mostly responsible for a diverse spectrum of invasive human and animal infections leading to the urinary tract infections. Bacterial lipopolysaccharides are responsible for their pathogenicity and their interactions with host immune responses. In spite of several breakthroughs in the development of therapeutics to combat urinary tract infections...

Glc3Man9(GlcNAc)2-pyrophosphoryl-dolichol is the major lipid-linked oligosaccharide (LLO) produced by Madin-Darby canine kidney cells in culture. However, when these cells are incubated in the presence of millimolar concentrations of mannosamine and labeled with [2-3H]mannose, they accumulate various LLO that have smaller-sized oligosaccharides with unusual structures and the Glc3Man9(GlcNAc)2-...

The structural elucidation of oligosaccharides remains a major challenge. Mass spectrometry provides a rapid and convenient method for structural elucidation based on tandem mass spectrometry. Ions commonly are selected and subjected to collision-induced dissociation (CID) to obtain structural information. Unfortunately, N-linked oligosaccharides are relatively large compounds and are not readi...

This study synthesized resveratrol oligosaccharides (gluco oligosaccharides) by two-step enzymatic glycosylation, using glucosyltransferase from Phytolacca americana and cyclodextrin glucanotransferase. Although hardly crosses the blood–brain barrier (BBB) in mouse brain, incorporated into brain tissue crossed BBB. Our indicated that modified with might have gained a BBB-crossing ability. Furth...