نتایج جستجو برای: utr
تعداد نتایج: 8278 فیلتر نتایج به سال:
مقدمه: خستگی ناحیه شانه از مهمترین فاکتورهای آغازگر اختلالات اسکلتی-عضلانی (musculoskeletal disorders: msds) در اندام فوقانی است و در بین قالی بافان، شایع ترین msdها در این ناحیه به وقوع می پیوندد. هدف از این مطالعه یافتن تأثیر قالی بافی در ایستگاه کاری پیشنهادی بر خستگی عضله ذوزنقه ای فوقانی (upper trapezius: utr) طی یک چرخه وظایف شغلی است. روش کار: در این مطالعه مقطعی 9 زن و 3 مرد مشارکت داش...
BACKGROUND Non Muscle Invasive Bladder Transitional Cancer (NMIBC) and Muscle Invasive Bladder Transitional Cancer (MIBC)/invasive have different gene profile and clinical course. NMIBC prognosis is not completely predictable, since the relapse rate is higher than 20%, even in the form of MIBC. The aim of this study is to evaluate if UTR expression can discriminate between NMIBC and MIBC and pr...
Long 3' untranslated regions (3'UTRs) are common in eukaryotic mRNAs. In contrast, long 3'UTRs are rare in bacteria, and have not been characterized in detail. We describe a 3'UTR of 310 nucleotides in hilD mRNA, a transcript that encodes a transcriptional activator of Salmonella enterica pathogenicity island 1 (SPI-1). Deletion of the hilD 3'UTR increases the hilD mRNA level, suggesting that t...
Translational regulation of ornithine decarboxylase (ODC), which catalyses the first step in the biosynthesis of polyamines, appears to be an important mechanism in the strong feedback control as well as in the hypotonic induction of the enzyme. However, the exact mechanisms are not yet understood. The ODC mRNA has long 5' and 3' untranslated regions (UTRs) which may be involved in the translat...
OBJECTIVES OCT4 is a transcription factor required for pluripotency during early embryogenesis and the maintenance of identity of embryonic stem cells and pluripotent cells. Therefore, the effective expression regulation of this gene is highly critical. UTR regions are of great significance to gene regulation. In this study, we aimed to investigate the potential regulatory role played by 5´UTR ...
زمینه: در انتهای5 /-utr ژن f سویه واکسن سرخک یک توالی غیر معمول طولانی غیرکد کننده قرار دارد که با توجه به موتاسیون ها و حذف های منطقه ای، تغییرات در این ناحیه می تواند بر عملکرد پروتئین f تولید شده مؤثر باشد. هدف: مطالعه به منظور تعیین ژنومیکس تغییرات توالی 5/-utr ژن f ویروس سرخک سوش واکسن aik-c تکثیر شده در سلول های mrc-5 انجام شد. مواد و روش ها: این پژوهش بنیادی در سال 1385 در بخش بیوتکنولوژ...
It has been hypothesized that both the 3'-untranslated region (3'UTR) and the 5'-untranslated region (5'UTR) of the ornithine decarboxylase (ODC) mRNA influence the expression of the ODC protein. Here, we use luciferase expression constructs to examine the influence of both UTRs in keratinocyte derived cell lines. The ODC 5'UTR or 3'UTR was cloned into the pGL3 control vector upstream or downst...
Mature messenger RNAs (mRNAs) consist of coding sequence (CDS) and 5' and 3' UTRs, typically expected to show similar abundance within a given neuron. Examining mRNA from defined neurons, we unexpectedly show extremely common unbalanced expression of cognate 3' UTR and CDS sequences; many genes show high 3' UTR relative to CDS, others show high CDS to 3' UTR. In situ hybridization (19 of 19 gen...
Most of the beta thalassaemia cases are heterogeneous at molecular level. The genetic variation arises due to mutation a single beta-globin gene (HBB) on chromosome 11p15.5. Eventhough, basis and natural history this disorder still not well understood clinical presentation in certain patients was always correlated with diagnosis [1].
 
 study aimed evaluate predisposing effect HBB pol...
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