newcastle disease (nd) is one of the most serious illnesses of chickens. live vaccines are widely used to prevent chicken from the disease all over the world. to access the effective and potentiate nd vaccine, a homogenous subpopulation from lasota strain was selected following cultivation of the virus on primary chicken embryofibroblast (cef) cells. pathogenicity indices and molecular characte...

this report describes the preparation of a safe and immunogenic single vaccine against capripox disease in sheep and goats using two different types of cells (primary lamb kidney and vero, a bovine turbinate cell line). this used the 0240 pox strain isolated from sheep during an outbreak. the prepared vaccine was administered subcutaneously and induced complete protection against an experimenta...

Seven children with acute disseminated encephalomyelitis (ADEM) after treatment with Japanese B encephalitis vaccine (JBEV) (Nakayama-Yoken strain 1968-88 and Beijing strain 1989-93) were identified by mailed questionnaires and by compilation of previously published case reports. It was considered that encephalomyelitis might have been related to vaccine treatment as the vaccine is derived from...

background: re-emergence of pertussis has been reported in iran despite a high rate of vaccination coverage. low efficacy of the vaccine might be due to the genetic divergence between clinical versus vaccine strains. in the current study, the genetic profiles of clinical isolates and vaccine strains of bordetella pertussis (b. pertussis) were assessed by using pulsed field gel electrophoresis (...

mycoplasma synoviae expressed variable lipoprotein haemagglutinin (vlha) is believed to play a major role in pathogenesis of the disease by mediating adherence and immune evasion. the aim of this study was sequencing iranian m. synoviae isolates for the detection of nucleotide variation in the m. synoviae vlha gene. using oligonucleotide primers complementary to the single-copy conserved 5´ end...

ten field isolates of mycoplasma gallisepticum (mg) from different geographical areas of iran were analyzed by random amplification of polymorphic dna (rapd). rapd analysis produced reproducible banding patterns on the basis of which various distinct amplification patterns could be detected. mg isolates compared with reference strains (s6 and mg ss) and vaccine strain (ts-11) and demonstrated d...

background bcg (bacille calmette-guerin) vaccine is an attenuated live vaccine administered to prevent tuberculosis. disseminated infection due to bcg is a rare life threatening complication of this vaccine, especially in immunocompromised patients. objectives the current study evaluated the sensitivity pattern of the bcg strain supplied by the institute de pasteur, iran against anti-mycobacter...

Poliomyelitis associated with live strain vaccine is defined as the paralytic form of the acute anterior poliomyelitis related to the vaccine strain. Since these strains behave similarly to the wild-type virus, we can differentiate, epidemiologically, two types of vaccine-associated poliomyelitis: cases in which the patient was vaccinated and cases in which the patient had had contact with vacc...

  Blackleg in cattle has been recognized since 1938 in Iran that mostly affects cattle in enzootic farm. Main object of this study was to prepare and formulate a concentrated potent vaccine for immunization of cattle against blackleg in Iran. Experimental concentrated blackleg vaccine was prepared according to the method described by FAO. The medium (Modified medium for production of experiment...

OBJECTIVE To identify a strain of contagious ecthyma virus from goats that possesses the appropriate characteristics for an effective vaccine for goats. ANIMALS 25 goat kids used for vaccine development and 100 goat kids used for evaluation of vaccine efficacy. PROCEDURES 5 strains of contagious ecthyma virus were tested in a vaccination-challenge study to identify the best strain to be the...