Novel therapeutic approaches are needed to combat the urinary tract infection in women. During menstruation elevated protein concentration and increase in oxygen and carbon dioxide concentrations with decrease in vaginal Lactobacilli all together contribute to urinary tract infections. Lactobacillus species are a predominant member of the vaginal microflora and are critical in the prevention of...

Presently marketed vaginal barrier agents are cytotoxic and damage the vaginal epithelium and natural vaginal flora with frequent use. Novel noncytotoxic agents are needed to protect women from sexually transmitted diseases. One candidate compound is a high-molecular-mass form of soluble poly(sodium 4-styrene sulfonate) (T-PSS). The antimicrobial activity of T-PSS was evaluated in primary cultu...

Introduction
 Hysterectomy is a reasonably safe, common and routine surgical procedure which rarely leads to perioperative death. Minor complications including postoperative infections, fever, wound hematomas or separation occur in approximately 25% of patients. 
 Objective A comparative assessment the post-operative outcomes Sri Lankan patients subjected Total Abdominal Ascending Vag...

Perspectives on Sexual and Reproductive Health “For decades before we had oral contraceptives, untold and unstudied millions of women used the vaginal diaphragm lubricated with spermicide as a contraceptive. They experienced no major ‘new’ epidemics of sexually transmitted diseases or pelvic inflammatory diseases but rather the opposite, and they probably also gained some protection against can...

Vaginal trichomonosis is a highly prevalent infection which has been associated with human immunodeficiency virus acquisition and preterm birth. Culture is the current "gold standard" for diagnosis. As urine-based testing using DNA amplification techniques becomes more widely used for other sexually transmitted diseases (STDs) such as gonorrhea and chlamydia, a similar technique for trichomonos...

OBJECTIVE The objective of this study was to compare histological and biochemical features of the (normal) precervical anterior vaginal wall and the prolapsed anterior vaginal wall of women with pelvic organ prolapse (POP). These data were compared to tissue of the precervical anterior vaginal wall of age-matched controls without POP to identify possible intrinsic and acquired effects. STUDY ...

Objective: To evaluate the applicability of the technique of vaginal hysterectomy in non-prolapsed uterus. Methods: A retrospective cohort study with 220 patients submitted to vaginal hysterectomy from January 2004 to July 2010 by the Vaginal Surgery and Pelvic Floor Team. Patients mean age was 44.4 years and they had on average three births (0-10 deliveries). The surgery was performed even in ...

BACKGROUND Serum CA-125 has been used as a biomarker of gynecological tumors. In this study, we investigated the CA-125 levels in cervical and vaginal secretions from Chinese patients with endometrial polyps, hyperplasia and carcinoma in comparison with those in endometrium and serum. MATERIAL/METHODS An electro-chemiluminescent immunoassay was utilized to determine the levels of CA-125 in 51...

OBJECTIVE Identification of the symptoms of bacterial vaginosis (BV) in pregnancy might be rational in order to identify a possible BV-associated group at risk of preterm delivery. METHODS Three hundred and five women early in the third trimester of pregnancy were interviewed about lifestyle factors and specific symptoms of BV and given a vaginal examination. A longitudinal three-week follow-...