In recent popular publications as well as in widely used information websites directed to cancer patients, valerian is claimed to have a potential of adverse interactions with anticancer drugs. This questions its use as a safe replacement for, for example, benzodiazepines. A review on the interaction potential of preparations from valerian root (Valeriana officinalis L. root) was therefore cond...

BACKGROUND Insomnia is an often seen primary health care problem. Valerian might be an alternative treatment with fewer secondary effects. The aim of this study is to evaluate its effectiveness on insomnia through a meta-analysis of published literature. METHODS Search for randomized clinical trials (RCTs) of Valerian preparations compared with a placebo on Medline, the Cochrane Library, Emba...

Abstract The anesthetic efficacy of Valerian ( Valeriana officinalis ) powders was evaluated on common carp Cyprinus carpio L.) following concentrations (250, 350, 450) mg/liter were used in three replicates. During the experiment, period required for partial and total anesthesia time recovery tested, as well number red white blood cells after before Anesthesia addition to serum enzymes represe...

Introduction: : It seems that Valeriana officinalis (valerian) extract through gamma-amino-butyric acid A (GABAA) receptor possesses analgesic effect. The aim of the present study was to investigate the effect of muscimol and picrotoxin on pain sensitivity in male rats pretreated with valerian extract using the formalin test. Methods: Thirty-five male rats weighing 200-250g in standard temp...

The 15th Baikal International School-Seminar on OPTIMIZATIONMETHODS AND THEIR APPLICATIONS is dedicated to the memory of Professor Valerian Pavlovich Bulatov.

In this research, the effects of electromagnetic fields of various strengths (0, 1 and 2mT) have been investigated on antioxidant enzymes activity in Valerian (Valeriana officinalis L.). The dry and wet (soaked for 30 min) Valerian seeds were exposed to electromagnetic fields 30 min per day for 3 days. Each treatment and control groups had 3 replicates and 10 seeds were employed for each replic...

Following the Civil War, American concern mounted about the anesthetic safety of ether and of chloroform. After reviving the use of nitrous oxide for brief anesthetics, dentists and physicians had to hurdle new obstacles. Because most nitrous oxide administrations lacked supplementary oxygen, a roughly 50-s inhalation of 100% laughing gas might yield as little as 30 s procedurally for tooth ext...

The clinical features and risk of hepatotoxicity of 'Sleep-Qik' (valerian dry extract 75 mg, hyoscine hydrobromide 0.25 mg, cyproheptadine hydrochloride 2 mg) were determined in 23 patients treated in our hospital between 1988 and 1991. The main clinical problems were central nervous system depression and anticholinergic poisoning. There was no clinical evidence of acute hepatitis in the 23 pat...