We compared contrast angiography with three techniques of quantitating valvular regurgitation from radionuclide ventriculograms in 70 patients: 45 with documented regurgitation graded 1-4+, and 25 without regurgitation. The radionuclide "regurgitant index" (ratio of L to R ventricular stroke counts) was measured from fixed end-diastolic regions of interest (method A), from separate end-diastoli...

BACKGROUND Although appetite suppressants have been implicated in the development of valvular heart disease, the exact level of risk is still uncertain. Initial studies suggested that as many as 1 in 3 exposed patients were affected, but subsequent research has yielded substantially different figures. Our objective was to systematically assess the risk of valvular heart disease with appetite su...

The ventricular dimensions of 51 patients with heart disease were determined by ultrasonic echography during cardiac catheterization. These data were used to calculate end-diastolic and end-systolic volumes and stroke volume, using a prolate ellipse as a geometric model of the left ventricle. In 30 patients without valvular regurgitation the stroke volumes determined by the echographic method w...

The following valvular disorders are considered here in the context of competitive athletes: mitral stenosis (MS), mitral regurgitation (MR), aortic stenosis (AS), aortic regurgitation (AR), tricuspid regurgitation (TR), tricuspid stenosis, and multivalvular disease. Recommendations are also provided for patients who have undergone valve repair or replacement. The diagnosis of valvular heart di...

The most common etiology of tricuspid stenosis is rheumatic, and in most cases it is associated with valvular regurgitation. Interestingly, there have been reports of tricuspid stenosis without associated valvular regurgitation, mostly related to pacemaker leads. Percutaneous tricuspid valvuloplasty may be a therapeutic alternative to surgery in cases of pure tricuspid stenosis without other co...

T HE shape of an indicator-dilution curve is determined by at least 4 variables: cardiac output, the volume between the injection site and the sampling site, the presence of a left-to-right intracardiac shunt, and the presence of valvular regurgitation.1-3 In the absence of an intracardiac shunt and valvular regurgitation, one can predict the downslope of the arterial dilution curve, using the ...

Doppler echocardiography (DE) is known to be a valuable tool for detecting subclinical forms of valvular regurgitation (VRJ in theacutephase of rheumatic fever (RF). Previous studies have mostly dealt with the acute phase problem with only short-term follow-up. In this study, 24 children between 4-15 years of age (mean age II.X±2.7 years) with RF without clinically diagnosed carditis (most ...

Pulsed Doppler echocardiography was employed to detect disturbed or turbulent flow diagnostic of aortic or mitral regurgitation. Sensitivity, specificity, diagnostic accuracy, and predictive value were assessed by the independent interpretation and comparison of aortic root angiograms (91 patients) and left ventriculograms (94 patients) to the time interval histogram display of the pulsed Doppl...

BACKGROUND Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical conditions imposed by pathologic valvular anatomy act on AF hemodynamics. METHODS We simulated AF with different severity grades of left-sided va...

AIMS Valvular heart disease (VHD), inducing valvular regurgitation, has been described in carcinoid heart disease and recently in Parkinson's patients treated with pergolide. The aim of this study was to develop an in vivo model of drug-induced valvulopathy with pergolide in rats. METHODS AND RESULTS Thirty male Wistar rats were given daily injections of either pergolide (0.5 mg/kg intraperit...