In the present study the upper reference limits (URLs) for resting plasma norepinephrine, epinephrine, serum aldosterone, plasma renin activity, aldosterone/renin activity ratio, as well as urinary vanillylmandelic acid in healthy Egyptian normotensive subjects over a range of ages (5-60 yr) were established. There was a significant age effect on plasma norepinephrine, UVMA, serum aldosterone a...

BACKGROUND The aerial parts of Vitis vinifera (common grape or European grape) have been widely used in Ayurveda to treat a variety of common and stress related disorders. In the present investigation, the seed extract of V. vinifera was evaluated for antistress activity in normal and stress induced rats. Furthermore, the extract was studied for nootropic activity in rats and in-vitro antioxida...

Background and objectives: The prevalence of anxiety disorders is increasing in the world. Studies revealed that generalized disorder may lead to change circulating catecholamine levels. Thus, changes metabolite like urinary vanillylmandelic acid increase future risk thrombotic diseases patients with (GAD). aim this present study evaluate (VMA) levels disorder. Materials methods: A cross-sectio...

called vanillylmandelic acid (VMA), in urine has recently come into use as a confirmatory test for pheochromocytoma (1-6). Armstrong and his associates (1, 2, 7) discovered that this phenolic acid occurred in small amounts in normal human urine and in elevated concentrations in pheochromocytoma. As a result of their observations (1, 2) and especially of those by others in related investigations...

This report describes the clinical and cytogenetic analysis of a kindred with multiple endocrine neoplasia type 2 (MEN-2 or Sipple's syndrome) in two generations. Medullary thyroid carcinoma was present in five members either as a large or as an occult tumour. Phaeochromocytoma was demonstrated in one severely hypertensive relative and urine vanillylmandelic acid (VMA) was increased in one norm...

We describe a simple liquid-chromatographic assay of urinary 4-hydroxy-3-methoxymandelic (vanillylmandelic) acid, 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid, and 5-hydroxy-3-indoleacetic acid with electrochemical detection, with direct injection of the sample. The first two analytes are measured simultaneously; 5-hydroxy-3-indoleacetic acid is measured separately. Chromatographic condi...